Protein Alignment Idh3b and LEU2

DIOPT Version :9

• Sequence 1: NP_001163682.1
• Gene: Idh3b / 42586
• FlyBaseID: FBgn0038922
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_009911.2
• Gene: LEU2 / 850342
• SGDID: S000000523
• Length: 364
• Species: Saccharomyces cerevisiae
• Alignment Length: 352
• Identity: 95/352 - (26%)
• Similarity: 176/352 - (50%)
• Gaps: 33/352 - (9%)

  Fly    42 LIPGDGVGPELVYSLQEVFKAAS-----VPVDFECYFL--SEINPVLSAKLEDVVASIQKNKVCI 99
            ::|||.||.|:.....:|.||.|     |..|||.:.:  :.|:.......::.:.:.:|....:
Yeast     9 VLPGDHVGQEITAEAIKVLKAISDVRSNVKFDFENHLIGGAAIDATGVPLPDEALEASKKADAVL 73

  Fly   100 KGVLATPDY--SNVGDLQTLNMKLRNDLDLYANV-------VHVRSLPGVKTRHT-NIDTVIIRE 154
            .|.:..|.:  .:|...|.| :|:|.:|.||||:       ..:..|..:|.:.. ..|.|::||
Yeast    74 LGAVGGPKWGTGSVRPEQGL-LKIRKELQLYANLRPCNFASDSLLDLSPIKPQFAKGTDFVVVRE 137

  Fly   155 QTEGEY-SALEHESVPGIVECLKIITAKKSMRIAKFAFDYATKNQRK-KVTAVHKANIMKLGDGL 217
            ...|.| ...:.:...|:....:..|..:..||.:.|...|.:::.. .:.::.|||:: ....|
Yeast   138 LVGGIYFGKRKEDDGDGVAWDSEQYTVPEVQRITRMAAFMALQHEPPLPIWSLDKANVL-ASSRL 201

  Fly   218 FLRSCEE-VSRLYPRIQFEKMIVDNTTMQMVSNPNQFD-VMVTPNLYGAIVDNLASGLVGGAGVV 280
            :.::.|| :...:|.::.:..::|:..|.:|.||...: :::|.|::|.|:.:.||.:.|..|::
Yeast   202 WRKTVEETIKNEFPTLKVQHQLIDSAAMILVKNPTHLNGIIITSNMFGDIISDEASVIPGSLGLL 266

  Fly   281 AGASYSS---ESVVF---EPGARHTFAEAVGKNVANPTAMLLCGVKLLR-HINLPTYGEIIQNAI 338
            ..||.:|   ::..|   ||  .|..|..:.||..||.|.:|....:|: .:|||..|:.|::|:
Yeast   267 PSASLASLPDKNTAFGLYEP--CHGSAPDLPKNKVNPIATILSAAMMLKLSLNLPEEGKAIEDAV 329

  Fly   339 NKVLNDGKVRTKDLGGQSTTQDFTRAI 365
            .|||:.| :||.||||.::|.:...|:
Yeast   330 KKVLDAG-IRTGDLGGSNSTTEVGDAV 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idh3b	NP_001163682.1	Iso_dh	37..369	CDD:294303	95/352 (27%)
LEU2	NP_009911.2	leuB	6..359	CDD:272939	95/352 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810