DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idh3b and IDH-III

DIOPT Version :9

Sequence 1:	NP_001163682.1	Gene:	Idh3b / 42586	FlyBaseID:	FBgn0038922	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_195290.1	Gene:	IDH-III / 829717	AraportID:	AT4G35650	Length:	368	Species:	Arabidopsis thaliana

Alignment Length:	353	Identity:	175/353 - (49%)
Similarity:	239/353 - (67%)	Gaps:	16/353 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 SLHTTSTLRATDNYGANRTTCTLIPGDGVGPELVYSLQEVFKAASVPVDFECYFLSEINPVLSAK 84
            ||..:.|.......||.||. |||||||:||.:..::::|.:|...||.||.|   |:...:...
plant    22 SLSRSITYMPRPGDGAPRTV-TLIPGDGIGPLVTGAVEQVMEAMHAPVHFERY---EVLGNMRKV 82

  Fly    85 LEDVVASIQKNKVCIKGVLATPDYSNVGDLQTLNMKLRNDLDLYANVVHVRSLPGVKTRHTNIDT 149
            .|:|:.|:::||||:||.||||   ..|.:.:|||:||.:||::|::|:..::||:.|||.|:|.
plant    83 PEEVIESVKRNKVCLKGGLATP---VGGGVSSLNMQLRKELDIFASLVNCINVPGLVTRHENVDI 144

  Fly   150 VIIREQTEGEYSALEHESVPGIVECLKIITAKKSMRIAKFAFDYATKNQRKKVTAVHKANIMKLG 214
            |:|||.||||||.||||.|||:||.||:||...|.|||::||:||..|.|||||||||||||||.
plant   145 VVIRENTEGEYSGLEHEVVPGVVESLKVITKFCSERIARYAFEYAYLNNRKKVTAVHKANIMKLA 209

  Fly   215 DGLFLRSCEEVSRLYPRIQFEKMIVDNTTMQMVSNPNQFDVMVTPNLYGAIVDNLASGLVGGAGV 279
            |||||.||.||::.|..|.:.::||||..||:|:.|.||||||||||||.::.|.|:|:.||.||
plant   210 DGLFLESCREVAKHYSGITYNEIIVDNCCMQLVAKPEQFDVMVTPNLYGNLIANTAAGIAGGTGV 274

  Fly   280 VAGASYSSESVVFEPGARHTFAEAVG------KNVANPTAMLLCGVKLLRHINLPTYGEIIQNAI 338
            :.|.:..:|..:||.||.   |..||      :..|||.|:||....:|||:..||:.:.::.|:
plant   275 MPGGNVGAEHAIFEQGAS---AGNVGNDKMVEQKKANPVALLLSSAMMLRHLRFPTFADRLETAV 336

  Fly   339 NKVLNDGKVRTKDLGGQSTTQDFTRAII 366
            .:|:.:||.|||||||..|||:...|:|
plant   337 KQVIKEGKYRTKDLGGDCTTQEVVDAVI 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idh3b	NP_001163682.1	Iso_dh	37..369	CDD:294303	170/336 (51%)
IDH-III	NP_195290.1	PLN00123	8..368	CDD:215065	175/353 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	331	1.000	Domainoid score	I260
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	335	1.000	Inparanoid score	I666
OMA	1	1.010	-	-		QHG53770
OrthoDB	1	1.010	-	-		D868374at2759
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101342
Panther	1	1.100	-	-	O	PTHR11835
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1965
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.840