DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idh3b and IDH-VI

DIOPT Version :9

Sequence 1:	NP_001163682.1	Gene:	Idh3b / 42586	FlyBaseID:	FBgn0038922	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_850549.1	Gene:	IDH-VI / 820139	AraportID:	AT3G09810	Length:	374	Species:	Arabidopsis thaliana

Alignment Length:	374	Identity:	170/374 - (45%)
Similarity:	241/374 - (64%)	Gaps:	13/374 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSMLA----RTVGRTFMQAAAARSLHTTSTLRATDNYGANRT--TCTLIPGDGVGPELVYSLQEV 59
            |:|.|    |.:|....|.....|..:...:..:..:.::.|  ..||.||||:|||:..|:::|
plant     1 MTMTAFLARRLIGNGSSQILGTSSSSSGPFISVSRAFFSSSTPIKATLFPGDGIGPEIAESVKQV 65

  Fly    60 FKAASVPVDFECYFL-SEINPVLSAKLE-DVVASIQKNKVCIKGVLATPDYSNVG-DLQTLNMKL 121
            |.||.|.:|::..|: :|::|..::.|. |.:.|:.||||.:||.:|||    :| ..::||:.|
plant    66 FTAADVVIDWDEQFVGTEVDPRTNSFLTWDNLQSVLKNKVGLKGPMATP----IGKGHRSLNLTL 126

  Fly   122 RNDLDLYANVVHVRSLPGVKTRHTNIDTVIIREQTEGEYSALEHESVPGIVECLKIITAKKSMRI 186
            |.:|:|||||....||||.|||:.::|.:.|||.||||||.|||:.|.|:||.|||||.|.|||:
plant   127 RKELNLYANVRPCYSLPGYKTRYDDVDLITIRENTEGEYSGLEHQVVKGVVESLKIITRKASMRV 191

  Fly   187 AKFAFDYATKNQRKKVTAVHKANIMKLGDGLFLRSCEEVSRLYPRIQFEKMIVDNTTMQMVSNPN 251
            |::||.||..:.||||:|:||||||:..|||||:.|:||:..||.|.:||:::||..|.:|.||.
plant   192 AEYAFLYAKTHGRKKVSAIHKANIMQKTDGLFLQCCDEVAAKYPEIYYEKVVIDNCCMMLVKNPA 256

  Fly   252 QFDVMVTPNLYGAIVDNLASGLVGGAGVVAGASYSSESVVFEPGARHTFAEAVGKNVANPTAMLL 316
            .|||:|.|||||.|:.:|.:|||||.|:....:...:.:........:..:..|.|:|||||:||
plant   257 LFDVLVMPNLYGDIISDLCAGLVGGLGLTPSMNIGEDGIALAEAVHGSAPDIAGMNLANPTALLL 321

  Fly   317 CGVKLLRHINLPTYGEIIQNAINKVLNDGKVRTKDLGGQSTTQDFTRAI 365
            .||.:|||:.|....|.|.:||...:.:||.||.||||.|||.|||:||
plant   322 SGVMMLRHLKLNKQAEQIHSAIINTIAEGKYRTADLGGSSTTTDFTKAI 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idh3b	NP_001163682.1	Iso_dh	37..369	CDD:294303	163/334 (49%)
IDH-VI	NP_850549.1	PLN00118	3..374	CDD:215062	169/372 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53770
OrthoDB	1	1.010	-	-		D868374at2759
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830