DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idh3b and idh3g

DIOPT Version :9

Sequence 1:	NP_001163682.1	Gene:	Idh3b / 42586	FlyBaseID:	FBgn0038922	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_001025597.1	Gene:	idh3g / 594985	XenbaseID:	XB-GENE-492840	Length:	395	Species:	Xenopus tropicalis

Alignment Length:	335	Identity:	176/335 - (52%)
Similarity:	239/335 - (71%)	Gaps:	7/335 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 YGANRTTCTLIPGDGVGPELVYSLQEVFKAASVPVDFECYFLSEINPVLSAK--LEDVVASIQKN 95
            || .|.|.|:|||||:||||:..::|||:.:.||:|||   :..:|...:.:  :::.:.:|::|
Frog    52 YG-GRHTVTMIPGDGIGPELMLHVKEVFRHSCVPIDFE---VVNVNSTSNDEDDIQNAITAIRRN 112

  Fly    96 KVCIKGVLATPDYSNVGDLQTLNMKLRNDLDLYANVVHVRSLPGVKTRHTNIDTVIIREQTEGEY 160
            :|.:||.:.| :::.....::.|..||..|||||||:|.||:|||:|||.:||.:|:||.|||||
Frog   113 RVALKGNIET-NHNMPPSHRSRNNLLRTSLDLYANVIHCRSVPGVQTRHKDIDIMIVRENTEGEY 176

  Fly   161 SALEHESVPGIVECLKIITAKKSMRIAKFAFDYATKNQRKKVTAVHKANIMKLGDGLFLRSCEEV 225
            |:||||||.|:||.|||||...|:|||::||..|.:..|||:|||||||||||||||||..|:||
Frog   177 SSLEHESVSGVVESLKIITRANSLRIAEYAFKLAREEGRKKITAVHKANIMKLGDGLFLACCKEV 241

  Fly   226 SRLYPRIQFEKMIVDNTTMQMVSNPNQFDVMVTPNLYGAIVDNLASGLVGGAGVVAGASYSSESV 290
            :..||.|.||.|||||||||:||||.||||||.|||||.||:|:.:|||||.|:|.||:|.:...
Frog   242 ASGYPDITFESMIVDNTTMQLVSNPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVPGANYGNVYA 306

  Fly   291 VFEPGARHTFAEAVGKNVANPTAMLLCGVKLLRHINLPTYGEIIQNAINKVLNDGKVRTKDLGGQ 355
            |||...|:|......||:||||||||....:|.|:.|.:|...|:.||...:|:.::.|.|:|||
Frog   307 VFETATRNTGKSIANKNIANPTAMLLASCMMLDHLKLHSYAASIRKAILGSMNEHRMHTADIGGQ 371

  Fly   356 STTQDFTRAI 365
            .||.:..::|
Frog   372 GTTSEVVQSI 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idh3b	NP_001163682.1	Iso_dh	37..369	CDD:294303	174/331 (53%)
idh3g	NP_001025597.1	mito_nad_idh	53..385	CDD:272942	175/334 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D325037at33208
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010