DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idh3b and CG32026

DIOPT Version :9

Sequence 1:	NP_001163682.1	Gene:	Idh3b / 42586	FlyBaseID:	FBgn0038922	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_729420.1	Gene:	CG32026 / 317829	FlyBaseID:	FBgn0052026	Length:	719	Species:	Drosophila melanogaster

Alignment Length:	341	Identity:	132/341 - (38%)
Similarity:	213/341 - (62%)	Gaps:	20/341 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 TLIPGDGVGPELVYSLQEVFKAASVPVDFECYFLSEINPVLSAK-----LEDVVASIQKNKVCIK 100
            ||:||||:|||:..::.::.:||..|:.||..   ::.|||:::     .|.|:.|:.:.||.:|
  Fly   386 TLMPGDGIGPEISMAVIKILEAAKTPLIFEPV---DVTPVLNSQGMTSVPEQVIESMNRTKVGLK 447

  Fly   101 GVLATPDYSNVG-DLQTLNMKLRNDLDLYANVVHVRSLPGVKTRHTNIDTVIIREQTEGEYSALE 164
            |.|.||    || ..::||:.||...:||||:...||||||:|.:.::|.|.|||.||||||.:|
  Fly   448 GPLMTP----VGTGFRSLNLTLRQLFNLYANIRPCRSLPGVETVYGDVDIVTIRENTEGEYSGIE 508

  Fly   165 HESVPGIVECLKIITAKKSMRIAKFAFDYATKNQRKKVTAVHKANIMKLGDGLFLRSCEEVSRLY 229
            |..|.|:|:.:|:||...|:|:|::.|.||...:|||||||.::.:|::.||||||...|::..|
  Fly   509 HTLVNGVVQSIKLITRNASLRVAEYTFQYALAMKRKKVTAVAESQVMRMSDGLFLRCVREMAAKY 573

  Fly   230 PR------IQFEKMIVDNTTMQMVSNPNQFDVMVTPNLYGAIVDNLASGLVGGAGVVAGASYSSE 288
            ..      |::|:..:....:.:|.:|.::|::|.|||||.|:.:..:||:||.|:....:..:.
  Fly   574 KSKMDQAGIKYEESTMTTVCLNIVQDPKRYDMLVLPNLYGDIISDTCAGLIGGLGLTPSGNVGTN 638

  Fly   289 SVVFEPGARHTFAEAVGKNVANPTAMLLCGVKLLRHINLPTYGEIIQNAINKVLNDGKVRTKDLG 353
            ..:|| ....|..:..||::|||||:||..|.:|.:|.|..:.:.|:.|:.|.:.|..:||.|||
  Fly   639 GAIFE-SVHGTAPDIAGKDLANPTALLLSSVMMLHYIGLHEHADKIEKAVLKTIRDDNIRTMDLG 702

  Fly   354 GQSTTQDFTRAIILNM 369
            |::...::|.|:|.|:
  Fly   703 GKAKCSEYTDALIKNL 718

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idh3b	NP_001163682.1	Iso_dh	37..369	CDD:294303	131/339 (39%)
CG32026	NP_729420.1	FGF-BP1	<281..361	CDD:284004
CG32026	NP_729420.1	Iso_dh	382..718	CDD:294303	131/339 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469786
Domainoid	1	1.000	180	1.000	Domainoid score	I145
eggNOG	1	0.900	-	-		E1_COG0473
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	181	1.000	Inparanoid score	I184
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D325037at33208
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	1	1.000	-	-		otm51400
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11835
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.900