Protein Alignment Idh3b and Idh3a

DIOPT Version :10

• Sequence 1: NP_651000.1
• Gene: Idh3b / 42586
• FlyBaseID: FBgn0038922
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_446090.2
• Gene: Idh3a / 114096
• RGDID: 70889
• Length: 366
• Species: Rattus norvegicus
• Alignment Length: 373
• Identity: 152/373 - (40%)
• Similarity: 213/373 - (57%)
• Gaps: 29/373 - (7%)

  Fly     1 MSMLARTVGRTFMQAAAARSLHTTSTLRATDNYGANRTTCTLIPGDGVGPELVYSLQEVFKAASV 65
            :|.::|.:|          :.|.|.  :.|..:.....|.|||||||:|||:..|:.::|.||..
  Rat     7 VSKVSRLLG----------AFHNTK--QVTRGFAGGVQTVTLIPGDGIGPEISASVMKIFDAAKA 59

  Fly    66 PVDFECYFLSEIN--------PVLSAKLEDVVASIQKNKVCIKGVLATPDYSNVGDLQTLNMKLR 122
            |:.:|...::.|.        |      .:...|:.|||:.:||.|.||   ......::|:.||
  Rat    60 PIQWEERNVTAIQGPGGKWMIP------PEAKESMDKNKMGLKGPLKTP---IAAGHPSMNLLLR 115

  Fly   123 NDLDLYANVVHVRSLPGVKTRHTNIDTVIIREQTEGEYSALEHESVPGIVECLKIITAKKSMRIA 187
            ...||||||....|:.|.||.:|:::.|.|||.||||||.:||..|.|:|:.:|:||...|.|||
  Rat   116 KTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIA 180

  Fly   188 KFAFDYATKNQRKKVTAVHKANIMKLGDGLFLRSCEEVSRLYPRIQFEKMIVDNTTMQMVSNPNQ 252
            :|||:||..|.|..||||||||||::.|||||:.|.||:.....|:|.:|.:|...:.||.:|:|
  Rat   181 EFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAENCKDIKFNEMYLDTVCLNMVQDPSQ 245

  Fly   253 FDVMVTPNLYGAIVDNLASGLVGGAGVVAGASYSSESVVFEPGARHTFAEAVGKNVANPTAMLLC 317
            |||:|.|||||.|:.:|.:||:||.||....:..:..|........|..:..||::|||||:||.
  Rat   246 FDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLS 310

  Fly   318 GVKLLRHINLPTYGEIIQNAINKVLNDGKVRTKDLGGQSTTQDFTRAI 365
            .|.:|||:.|..:...|:.|....:.|||..||||||.|...|||..|
  Rat   311 AVMMLRHMGLFDHAAKIEAACFATIKDGKSLTKDLGGNSKCSDFTEEI 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idh3b	NP_651000.1	Iso_dh	37..369	CDD:444908	146/337 (43%)
Idh3a	NP_446090.2	mito_nad_idh	29..362	CDD:272942	146/339 (43%)