Protein Alignment Theg and THEGL

DIOPT Version :9

• Sequence 1: NP_650999.1
• Gene: Theg / 42585
• FlyBaseID: FBgn0038921
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: XP_011532659.1
• Gene: THEGL / 100506564
• HGNCID: 43771
• Length: 486
• Species: Homo sapiens
• Alignment Length: 320
• Identity: 79/320 - (24%)
• Similarity: 119/320 - (37%)
• Gaps: 96/320 - (30%)

  Fly    89 PKSIEMVRPCDAQNHTRTEQLALPTVRRLLHRRRTAIL--AGDSIGESILNRWLRYSYLS-LYSR 150
            ||.::...|...: |||..       |:....:.|.:|  |...|..|::.|......|| |.:.
Human   110 PKLLKAREPRQLR-HTREP-------RKSREAKETELLPSAAVMISPSLITRAPPRPQLSFLGAN 166

  Fly   151 LTNIQPLVKPKKKKKKTEKQLAKHEKYIEKLAKPKKAPKVPKPDRGA--GEFDPV---------- 203
            ..:...:.|....:|:|           ..|:||||  :...|||..  |..||:
Human   167 PVSCDFVRKCFSSRKRT-----------PNLSKPKK--QWGTPDRKLFWGNQDPIRPVSQGALKA 218

  Fly   204 ----RLNQLASPKAYLEEIKPK--------------WELTSQMKDYKATKRIKQISQP------- 243
                ||..||.||.......|.              ||:|......:.:|||:::|||
Human   219 QLTKRLENLAQPKEVSCHYVPNRAQYYHSCGRESVIWEITPPALFRQPSKRIQRLSQPNGFKRQC 283

  Fly   244 ---------VVRDNVHINENPEKVSPNALRYKPSARIKEMSEPLTTRDANQGLADVKENPFGIAP 299
                     ..||::.|::             ||.||.::|   ..:..:......|:....|:.
Human   284 LLNRPFSDNSARDSLRISD-------------PSPRILQLS---VAKGTDPNYHPSKKMQTKISL 332

  Fly   300 NALKYKASTRIKELAEPK--------EFENTHIRENPFAISPAALKAKASPRLIELAKPK 351
            :.|...|:.||.|||.|:        |.:.:.:...|  :.|||:.||.|||.|.|||.|
Human   333 STLSAIATPRIIELAHPRIKLEGLCYERQRSELPIRP--VPPAAMIAKPSPRTIALAKSK 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Theg	NP_650999.1	THEG	222..277	CDD:291573	17/70 (24%)
		THEG	296..351	CDD:291573	23/62 (37%)
THEGL	XP_011532659.1	THEG	175..231	CDD:291573	18/68 (26%)
		THEG	210..277	CDD:291573	15/66 (23%)
		THEG	255..311	CDD:291573	16/68 (24%)
		THEG	330..390	CDD:291573	23/61 (38%)
		THEG	369..426	CDD:291573	14/24 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147967
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15901
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	4	3.900