DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Qsox2 and QSOX1

DIOPT Version :9

Sequence 1:	NP_650998.1	Gene:	Qsox2 / 42583	FlyBaseID:	FBgn0038919	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_172955.1	Gene:	QSOX1 / 838067	AraportID:	AT1G15020	Length:	528	Species:	Arabidopsis thaliana

Alignment Length:	581	Identity:	136/581 - (23%)
Similarity:	221/581 - (38%)	Gaps:	188/581 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 TLLYCLLLISPADVLGRLNARKSAN----EASLYSD--------TDNVIMLDIESLRPALNLKNS 59
            :|::..||      ||.|:...:|:    ..|:..|        .||.|.|:..:.........:
plant     2 SLIHLFLL------LGLLSLEAAASFSPGSRSILRDIGSNVADQKDNAIELNATNFDSVFQDSPA 60

  Fly    60 K--LVQFLNSFCGDCHRFAPVFKTLSRDLYK-----WRRILRIYAVDCAQERNAQLCREFNIRQT 117
            |  :::|...:|..|..:.|.::.::| |:.     :..::.:..||||.:.|.:||.:|:|...
plant    61 KYAVLEFFAHWCPACRNYKPHYEKVAR-LFNGADAVYPGVVLMTRVDCAIKMNVKLCDKFSINHY 124

  Fly   118 PSLRFFGPDMRKNDDVLGAVIPGQDPEFISSTLAELVSQNDYGPGQPNFRPLKATDYEIFQDQDG 182
            |.| |:.|..|                |:..:         :||.|                :..
plant   125 PML-FWAPPKR----------------FVGGS---------WGPKQ----------------EKN 147

  Fly   183 ETPIQFVALVLQPKNSKIGRDTLLELLPFKELSVRIIEDSQIFNEFGLGPDDQKLAIVDRNGTAQ 247
            |     :::|.:.:.:    |.||..:           :.||.:.:||  |||||
plant   148 E-----ISVVNEWRTA----DLLLNWI-----------NKQIGSSYGL--DDQKL---------- 180

  Fly   248 YLTPSSDSSEAYASTIGDFLKNRNIQPDPPLPIAVAPNFTEFLDHQNQAILTKVLTPPLQVYRAD 312
                            |:.|.|.:.|                 :..:|||.             |
plant   181 ----------------GNLLSNISDQ-----------------EQISQAIF-------------D 199

  Fly   313 LEQAIDKLLHIELRKWVLLEGNSLNALKNIIKIFRYLNPL---------NKDGKLLLTDLDNSLS 368
            :|:|.::...|      :|...::.:.:......|:|..|         ......:|.:.|:...
plant   200 IEEATEEAFDI------ILAHKAIKSSETSASFIRFLQLLVAHHPSRRCRTGSAEILVNFDDICP 258

  Fly   369 SKQSIKGADFGDLVDSLEN----GRRVFKARRYVGCIGSRPLLRSFTCSMWTLFHHLTVEAAKPP 429
            |.:.....:.| ..|||.|    |:.|.:. .|..|.||:...|.|:|.:|.|.|.|:|......
plant   259 SGECSYDQESG-AKDSLRNFHICGKDVPRG-YYRFCRGSKNETRGFSCGLWVLMHSLSVRIEDGE 321

  Fly   430 NYFEAGSILKTFHGFAKYFFGCTDCSEHFQQMAIRRNLTSVKTHDEE----ILWLWAAHNEVNAR 490
            :.|...:|.    .|...||.|.||..||..|.:     ||||..::    .||||:.||:||.|
plant   322 SQFAFTAIC----DFINNFFMCDDCRRHFHDMCL-----SVKTPFKKARDIALWLWSTHNKVNER 377

  Fly   491 IAGD----STEDPKFPKIQFPSAENCPTCRSNDSE----WRTDEVLKYLKQLYDINNVSFY 543
            :..|    .|.||||||:.:|..:.||:|..:.:|    |..|:|.|:||:.|....||.|
plant   378 LKKDEDSLGTGDPKFPKMIWPPKQLCPSCYLSSTEKNIDWDHDQVYKFLKKYYGQKLVSVY 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Qsox2	NP_650998.1	PDI_a_QSOX	40..152	CDD:239290	26/118 (22%)
Qsox2	NP_650998.1	Evr1_Alr	413..504	CDD:282612	36/98 (37%)
QSOX1	NP_172955.1	PDI_a_QSOX	41..161	CDD:239290	32/171 (19%)
QSOX1	NP_172955.1	Evr1_Alr	305..394	CDD:282612	35/97 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	65	1.000	Domainoid score	I3612
eggNOG	1	0.900	-	-		E1_KOG1731
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1610
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D498515at2759
OrthoFinder	1	1.000	-	-		FOG0001506
OrthoInspector	1	1.000	-	-		mtm1146
orthoMCL	1	0.900	-	-		OOG6_102428
Panther	1	1.100	-	-	O	PTHR22897
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1232
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.870