DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Qsox2 and qsox1

DIOPT Version :9

Sequence 1:	NP_650998.1	Gene:	Qsox2 / 42583	FlyBaseID:	FBgn0038919	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	XP_002937004.1	Gene:	qsox1 / 613045	XenbaseID:	XB-GENE-944881	Length:	741	Species:	Xenopus tropicalis

Alignment Length:	540	Identity:	161/540 - (29%)
Similarity:	265/540 - (49%)	Gaps:	63/540 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 NEASLYSDTDNVIMLDIESLRPALNLKNSKLVQFLNSFCGDCHRFAPVFKTLSRDLYKWRRILRI 95
            :.|.||:..:.|:.||.::....|..::..:.:|..|:||.|.||.|.:..|:.|:..||.::.:
Frog    22 SHAGLYTPDEPVVHLDRKAHTYLLGSRSFWVAEFYASWCGHCQRFKPSWSGLAEDIKDWRPVVYL 86

  Fly    96 YAVDCAQERNAQLCREFNIRQTPSLRFFGPDMRK-----NDDVLGAVIPGQDPEFISSTLAELVS 155
            ..:|||:..|.:.|.||.:...|:::.|....::     ::|.:.:|     .....:.:..|..
Frog    87 GVIDCAESSNFETCNEFGVEGYPTIKSFKSFTKEVSQGVSEDAVHSV-----QALRENIITRLEE 146

  Fly   156 QNDYGPGQ-PNFRPLKATDYEIFQDQDGETPIQFVALVLQPKNSKIGRDTLLELLPFKELSVRII 219
            |.|..|.. |...|:...:.|.|.....|   .::||:.:..:..|||:|.|:::.::.:|||.:
Frog   147 QKDSRPSSWPPLEPISTFEVENFFKTKQE---NYLALIFEEPSMYIGRETTLDMVQYEGVSVRRV 208

  Fly   220 --EDSQIFNEFGLGPDDQKLAIVDRNGTAQYLTPSSDSSEAYASTIGDFLKNRNIQPDPPLP--- 279
              :.:.:.|:|.: .....|.::.|||:...:...:|:..:|.    |||::        ||
Frog   209 LRDQNDMVNKFWI-TSYPSLVLLSRNGSNTVVNLKADTRSSYT----DFLRS--------LPGVR 260

  Fly   280 ------IAVAPNFTEFLDHQNQAILTKVLTPPLQVYRADLEQAIDKLLHIELRKWVLLEGNSLNA 338
                  |.||.|.|...|.:..|..||       :|.||||.|:...|..|:.::..|||..|:|
Frog   261 KKNLFIIGVANNGTTEQDDRRIADSTK-------LYMADLESAVHYTLRAEVSRFSHLEGERLDA 318

  Fly   339 LKNIIKIFRYLNPLNKDGKLLLTDLDNSLSSK--QSIKGADFGDLVDSLENGRR--VFKARRYVG 399
            |...:.:.|...|....|..||..:.:.|..:  :.:...||.:::::.:..:.  :..:..||.
Frog   319 LIAYVSVLRKYFPARPYGTTLLKSIHSWLHDRAGKEVLYKDFENVLNNKDEAQNAVLSSSVNYVW 383

  Fly   400 CIGSRPLLRSFTCSMWTLFHHLTVEA----AKPPNYFEAGSILKTFHGFAKYFFGCTDCSEHFQQ 460
            |.||.|..|.|.||:|||||.|||:|    |.||.     .:|....|:.|.||||.:|:.||:.
Frog   384 CQGSHPNFRGFPCSLWTLFHFLTVQASEDTAAPPT-----EVLLGLRGYVKNFFGCRECAGHFES 443

  Fly   461 MAIRRNLTSVKTHDEEILWLWAAHNEVNARIAGDSTEDPKFPKIQFPSAENCPTCRSNDS----E 521
            || ..::.:|.|.||.|||||..||.||.|:||..:|||:|||:.:||...||.|:..|.    .
Frog   444 MA-AESMNTVNTLDEAILWLWDRHNRVNKRLAGQPSEDPEFPKLPWPSKTLCPFCQVEDGGDELA 507

  Fly   522 WRTDEVLKYLKQLYDINNVS 541
            |....||.::|..|...|::
Frog   508 WDIPNVLNFMKTHYSRQNLA 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Qsox2	NP_650998.1	PDI_a_QSOX	40..152	CDD:239290	27/116 (23%)
Qsox2	NP_650998.1	Evr1_Alr	413..504	CDD:282612	46/94 (49%)
qsox1	XP_002937004.1	PDI_a_QSOX	31..142	CDD:239290	27/115 (23%)
		QSOX_Trx1	152..259	CDD:375557	29/122 (24%)
		FAD_SOX	284..387	CDD:375797	27/109 (25%)
		Evr1_Alr	396..488	CDD:368111	48/97 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	118	1.000	Domainoid score	I5773
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	258	1.000	Inparanoid score	I3055
OMA	1	1.010	-	-		QHG48718
OrthoDB	1	1.010	-	-		D158783at33208
OrthoFinder	1	1.000	-	-		FOG0001506
OrthoInspector	1	1.000	-	-		mtm9402
Panther	1	1.100	-	-	O	PTHR22897
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1232
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080