DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Qsox3 and qsox1

DIOPT Version :9

Sequence 1:	NP_650997.1	Gene:	Qsox3 / 42582	FlyBaseID:	FBgn0038918	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	XP_002937004.1	Gene:	qsox1 / 613045	XenbaseID:	XB-GENE-944881	Length:	741	Species:	Xenopus tropicalis

Alignment Length:	547	Identity:	159/547 - (29%)
Similarity:	270/547 - (49%)	Gaps:	47/547 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 IILILIVQEGHSKQRCLDEEPPLYSKEDNIHVVVGASLKKILAEPAMGKLVQFLNSYCGNCRRFA 77
            ::|:..|...|:.....||  |:...:...|..:..|....:||        |..|:||:|:||.
Frog    13 LVLLATVVPSHAGLYTPDE--PVVHLDRKAHTYLLGSRSFWVAE--------FYASWCGHCQRFK 67

  Fly    78 HTFRKMAVDLQKWNRVLRIYAVDCARLENVKLCRDFRITLTPTIRYYPSKFQRIRHGIGTDIETT 142
            .::..:|.|::.|..|:.:..:|||...|.:.|.:|.:...|||:.:.|..:.:..|:..|...:
Frog    68 PSWSGLAEDIKDWRPVVYLGVIDCAESSNFETCNEFGVEGYPTIKSFKSFTKEVSQGVSEDAVHS 132

  Fly   143 IPSEIADQLIESLSENDYSESKGVKPIFDPIEPGNKLNDIYEQFDNKVTYILLVHPVDMGIETIL 207
            :.: :.:.:|..|.|...|......|: :||......|....:.:|.:..|.....:.:|.||.|
Frog   133 VQA-LRENIITRLEEQKDSRPSSWPPL-EPISTFEVENFFKTKQENYLALIFEEPSMYIGRETTL 195

  Fly   208 NMLPYPDVGV-RIIKDA-EMFAQFGLKPCKQMVALLNRSGKAQLIKPAGKSSSAYVE---SVAGL 267
            :|:.|..|.| |:::|. :|..:|.:.....:| ||:|:|...::.....:.|:|.:   |:.|:
Frog   196 DMVQYEGVSVRRVLRDQNDMVNKFWITSYPSLV-LLSRNGSNTVVNLKADTRSSYTDFLRSLPGV 259

  Fly   268 LHQN----GHTSMPTLPPAEPEYILSEGYDAFIVDYVLNSTKVLFQADLEQAIYQFLHVEIPKTA 328
            ..:|    |..:..|          :|..|..|.|    ||| |:.||||.|::..|..|:.:.:
Frog   260 RKKNLFIIGVANNGT----------TEQDDRRIAD----STK-LYMADLESAVHYTLRAEVSRFS 309

  Fly   329 FISGFKFKALRHIIRLFRRFNVLNRDGRRMLNSLVNHLFEVT--EITGEEFRDVVDDLQTRLDPI 391
            .:.|.:..||...:.:.|::......|..:|.|:.:.|.:..  |:..::|.:|:::.....:.:
Frog   310 HLEGERLDALIAYVSVLRKYFPARPYGTTLLKSIHSWLHDRAGKEVLYKDFENVLNNKDEAQNAV 374

  Fly   392 FAEQ-QYVGCLGSTPHTRRFSCSLWTLFHYFTVLAAQMKVYPPSSVTIGLYGLAKFFYDCKDGSM 455
            .:.. .||.|.||.|:.|.|.||||||||:.||.|::....||:.|.:||.|..|.|:.|::.:.
Frog   375 LSSSVNYVWCQGSHPNFRGFPCSLWTLFHFLTVQASEDTAAPPTEVLLGLRGYVKNFFGCRECAG 439

  Fly   456 YFVKL-AKRMNIAKVRTHDEEILWLWEAHNEVNEKLAGDASGDPRFPKVQFPERKHCPDCYTHSG 519
            :|..: |:.||  .|.|.||.|||||:.||.||::|||..|.||.|||:.:|.:..||.|....|
Frog   440 HFESMAAESMN--TVNTLDEAILWLWDRHNRVNKRLAGQPSEDPEFPKLPWPSKTLCPFCQVEDG 502

  Fly   520 ----EFDRDEVLKYLKRVYNLSYLSGD 542
                .:|...||.::|..|:...|:.|
Frog   503 GDELAWDIPNVLNFMKTHYSRQNLAND 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Qsox3	NP_650997.1	PDI_a_QSOX	40..153	CDD:239290	27/112 (24%)
Qsox3	NP_650997.1	Evr1_Alr	413..503	CDD:282612	44/90 (49%)
qsox1	XP_002937004.1	PDI_a_QSOX	31..142	CDD:239290	29/121 (24%)
		QSOX_Trx1	152..259	CDD:375557	26/108 (24%)
		FAD_SOX	284..387	CDD:375797	26/107 (24%)
		Evr1_Alr	396..488	CDD:368111	46/93 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	51	1.000	Domainoid score	I11371
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48718
OrthoDB	1	1.010	-	-		D158783at33208
OrthoFinder	1	1.000	-	-		FOG0001506
OrthoInspector	1	1.000	-	-		mtm9402
Panther	1	1.100	-	-	O	PTHR22897
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1232
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.030