DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Qsox3 and Qsox2

DIOPT Version :9

Sequence 1:	NP_650997.1	Gene:	Qsox3 / 42582	FlyBaseID:	FBgn0038918	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_650998.1	Gene:	Qsox2 / 42583	FlyBaseID:	FBgn0038919	Length:	552	Species:	Drosophila melanogaster

Alignment Length:	553	Identity:	221/553 - (39%)
Similarity:	333/553 - (60%)	Gaps:	42/553 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LTCIILILIVQE-GHSKQRCLDEEPPLYSKEDNIHVVVGASLKKILAEPAM----GKLVQFLNSY 69
            |.|::||..... |....|....|..|||..||:.::...||:     ||:    .||||||||:
  Fly     9 LYCLLLISPADVLGRLNARKSANEASLYSDTDNVIMLDIESLR-----PALNLKNSKLVQFLNSF 68

  Fly    70 CGNCRRFAHTFRKMAVDLQKWNRVLRIYAVDCARLENVKLCRDFRITLTPTIRYYPSKFQRIRHG 134
            ||:|.|||..|:.::.||.||.|:|||||||||:..|.:|||:|.|..||::|::....::....
  Fly    69 CGDCHRFAPVFKTLSRDLYKWRRILRIYAVDCAQERNAQLCREFNIRQTPSLRFFGPDMRKNDDV 133

  Fly   135 IGTDIETTIPSEIADQLIESLSENDYSESKGVKPIFDPIEPGNKLNDIYEQFDNK-----VTYIL 194
            :|..|....|..|:..|.|.:|:|||...   :|.|.|:    |..| ||.|.::     :.::.
  Fly   134 LGAVIPGQDPEFISSTLAELVSQNDYGPG---QPNFRPL----KATD-YEIFQDQDGETPIQFVA 190

  Fly   195 LV-HPVD--MGIETILNMLPYPDVGVRIIKDAEMFAQFGLKPCKQMVALLNRSGKAQLIKPAGKS 256
            || .|.:  :|.:|:|.:||:.::.||||:|:::|.:|||.|..|.:|:::|:|.||.:.|:..|
  Fly   191 LVLQPKNSKIGRDTLLELLPFKELSVRIIEDSQIFNEFGLGPDDQKLAIVDRNGTAQYLTPSSDS 255

  Fly   257 SSAYVESVAGLLHQNGHTSMPTLP----PAEPEYILSEGYDAFIVDYVLNSTKVLFQADLEQAIY 317
            |.||..::...|........|.||    |...|::  :..:..|:..||.....:::|||||||.
  Fly   256 SEAYASTIGDFLKNRNIQPDPPLPIAVAPNFTEFL--DHQNQAILTKVLTPPLQVYRADLEQAID 318

  Fly   318 QFLHVEIPKTAFISGFKFKALRHIIRLFRRFNVLNRDGRRMLNSLVNHLFEVTEITGEEFRDVVD 382
            :.||:|:.|...:.|....||::||::||..|.||:||:.:|..|.|.|.....|.|.:|.|:||
  Fly   319 KLLHIELRKWVLLEGNSLNALKNIIKIFRYLNPLNKDGKLLLTDLDNSLSSKQSIKGADFGDLVD 383

  Fly   383 DLQTRLDPIFAEQQYVGCLGSTPHTRRFSCSLWTLFHYFTVLAAQMKVYPPS-----SVTIGLYG 442
            .|:.. ..:|..::||||:||.|..|.|:||:|||||:.||.||:    ||:     |:....:|
  Fly   384 SLENG-RRVFKARRYVGCIGSRPLLRSFTCSMWTLFHHLTVEAAK----PPNYFEAGSILKTFHG 443

  Fly   443 LAKFFYDCKDGSMYFVKLAKRMNIAKVRTHDEEILWLWEAHNEVNEKLAGDASGDPRFPKVQFPE 507
            .||:|:.|.|.|.:|.::|.|.|:..|:||||||||||.||||||.::|||::.||:|||:|||.
  Fly   444 FAKYFFGCTDCSEHFQQMAIRRNLTSVKTHDEEILWLWAAHNEVNARIAGDSTEDPKFPKIQFPS 508

  Fly   508 RKHCPDCYTHSGEFDRDEVLKYLKRVYNLSYLS 540
            .::||.|.::..|:..||||||||::|:::.:|
  Fly   509 AENCPTCRSNDSEWRTDEVLKYLKQLYDINNVS 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Qsox3	NP_650997.1	PDI_a_QSOX	40..153	CDD:239290	49/116 (42%)
Qsox3	NP_650997.1	Evr1_Alr	413..503	CDD:282612	48/94 (51%)
Qsox2	NP_650998.1	PDI_a_QSOX	40..152	CDD:239290	49/116 (42%)
Qsox2	NP_650998.1	Evr1_Alr	413..504	CDD:282612	48/94 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469393
Domainoid	1	1.000	65	1.000	Domainoid score	I3612
eggNOG	1	0.900	-	-		E1_KOG1731
Homologene	1	1.000	-	-		H65608
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1610
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D158783at33208
OrthoFinder	1	1.000	-	-		FOG0001506
OrthoInspector	1	1.000	-	-		mtm6583
orthoMCL	1	0.900	-	-		OOG6_102428
Panther	1	1.100	-	-	P	PTHR22897
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1232
	12	11.800