DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Qsox3 and F47B7.2

DIOPT Version :9

Sequence 1:	NP_650997.1	Gene:	Qsox3 / 42582	FlyBaseID:	FBgn0038918	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_001370700.1	Gene:	F47B7.2 / 180664	WormBaseID:	WBGene00018533	Length:	678	Species:	Caenorhabditis elegans

Alignment Length:	571	Identity:	144/571 - (25%)
Similarity:	253/571 - (44%)	Gaps:	71/571 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LTCIILILIVQEGHSKQRCL-DEEPPLYSKE-DNIHVVVGASLKKILAEPAMGKLVQFLNSYCGN 72
            |..:::||....|.|....| |::.|:...: |.....:..|.|        ...::|.:|:||.
Worm    24 LFILVVILAFSAGGSSGESLYDKDDPILELDVDTFSAAIYGSKK--------AHFIEFYSSWCGA 80

  Fly    73 CRRFAHTFRKMAVDLQKWNRVLRIYAVDCARLENVKLCRDFRITLTPTIRYYP----SKFQRIRH 133
            |..:|.||:|.|..|:||..::::..|:||..:|:.|||:..::..|::||:.    :|...:::
Worm    81 CIGYAPTFKKFAKQLEKWAPLVQVTVVNCADDKNMPLCREHSVSSYPSLRYFKYNSHNKDDGMKY 145

  Fly   134 -GIGTDIETTIPSEIADQLIESLSENDYSESKGVKPIFDPIEPGNKLNDIYEQFDNKVTYILLVH 197
             |...|| ..:..:||. |.::.::....||   .|.|.|:.....|.::::.. ...:|:.:|.
Worm   146 SGDKYDI-NKLAHDIAG-LAQADAQKQNPES---WPTFLPLSDTTTLEEVFKSI-GTTSYLAIVV 204

  Fly   198 PVDMGIETILNMLPY-PDVGVRIIK-------DAEMFAQFGLKPCKQMVALLNRSGKAQLIKPAG 254
            .....:....|::.| .:.||::..       ..:.|:..|:.      |||..:|..:   |..
Worm   205 QDSPSVIAWANLINYHGNNGVKVAYVTQNHPIATKFFSDGGVH------ALLFSNGNQE---PLW 260

  Fly   255 KSSSA------YVESVAGLLHQNGHTSMPTLPP-------AEPEYILSEGYDAFIVDYVLNSTKV 306
            ||||.      ..:.:..|:......|.||:.|       |.|...|:..|:..:|
Worm   261 KSSSPVDKWVDVQDKIDELIGDKIAASGPTVHPINAAPVIAAPSNPLNNQYEVQLV--------- 316

  Fly   307 LFQADLEQAIYQFLHVEIPKTAFISGFKFKALRHIIRLFRRFNVLNRDGRRMLNSLVNHLFEVTE 371
                ||:.|:...|:.|||:...|.......|:..:...:::.......||:...|...:...:.
Worm   317 ----DLKSAMSYMLYKEIPRREEIRDEPMAVLKQWMHTLKKYAPGTTPMRRLFFRLDEWIQLQSV 377

  Fly   372 ITGEEFRDVVDDLQTRL-DPIFAEQQYVGCLGSTPHTRRFSCSLWTLFHYFTVLAAQMKVY---- 431
            :|..|:...||::|..| :|:..|..::.|.||.|:.|.::|.||||.|..||.|.:.:.:
Worm   378 VTANEWITKVDEIQQALGNPLPKEITWMACAGSKPNLRGYTCGLWTLAHTITVEAYKQEKHNTAF 442

  Fly   432 -PPSSVTIGLYGLAKFFYDCKDGSMYFVKLAKRMNIAKVRTHDEEILWLWEAHNEVNEKLAGDAS 495
             |...|..........|..|.:.:..|.|.|::..:..|...::...|||..||.||::|:|..:
Worm   443 KPVIDVLEPFRAFIFHFLSCSECAQNFTKEAEKNQLHLVTRPEDVYAWLWRVHNFVNKRLSGSLT 507

  Fly   496 GDPRFPKVQFPERKHCPDCYTHSGEFDRDEVLKYLKRVY-NLSYLSGDAEP 545
            .||.|.|.|||.:..|.|||..:|:.|..:.|.::.:.| |:...|.|..|
Worm   508 DDPSFKKQQFPPKSLCADCYDANGDIDEAKALPFVFKYYSNIKTDSTDNLP 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Qsox3	NP_650997.1	PDI_a_QSOX	40..153	CDD:239290	33/117 (28%)
Qsox3	NP_650997.1	Evr1_Alr	413..503	CDD:282612	28/94 (30%)
F47B7.2	NP_001370700.1	PDI_a_QSOX	48..161	CDD:239290	32/121 (26%)
		FAD_SOX	317..410	CDD:408171	21/92 (23%)
		Evr1_Alr	420..515	CDD:398444	28/94 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	221	1.000	Inparanoid score	I2279
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48718
OrthoDB	1	1.010	-	-		D158783at33208
OrthoFinder	1	1.000	-	-		FOG0001506
OrthoInspector	1	1.000	-	-		mtm4857
orthoMCL	1	0.900	-	-		OOG6_102428
Panther	1	1.100	-	-	O	PTHR22897
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1232
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.980