Protein Alignment CG6678 and RCCD1

DIOPT Version :10

• Sequence 1: NP_650996.1
• Gene: CG6678 / 42581
• FlyBaseID: FBgn0038917
• Length: 373
• Species: Drosophila melanogaster
• Sequence 2: NP_291022.2
• Gene: RCCD1 / 91433
• HGNCID: 30457
• Length: 376
• Species: Homo sapiens
• Alignment Length: 403
• Identity: 126/403 - (31%)
• Similarity: 172/403 - (42%)
• Gaps: 87/403 - (21%)

  Fly     7 GFNAFGQHECVSGDVDCAAGFSELNAPVSTQNQCTISIGWRYAA-LAFGRKLCLRGLLDDGPNEC 70
            ||..||| |..||........|.|.|.|..   |.:|..|.|.| :..|.:|.|.|........|
Human    13 GFCGFGQ-ELGSGRGRQVHSPSPLRAGVDI---CRVSASWSYTAFVTRGGRLELSGSASGAAGRC 73

  Fly    71 VTLEATGNIRALAAADSHCLVLLQ---SGQLYRVQPKLQAELVAVRLEA----APRSNSGTKRSI 128
            ....|:..:.|:..|......|||   :....|.:| |.|:.|....|.    |..:.:| :..:
Human    74 KDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEP-LWAQNVVPEAEGEDDPAGEAQAG-RLPL 136

  Fly   129 FGAAKA---PSSPIIEHIACGSHINVAISSENCVYSIPSCLHQFSERQFRVKQLQCGHEHAVLLN 190
            ...|:|   |.:|....:|                           .:.|.:||:.|.|||:||:
Human   137 LPCARAYVSPRAPFYRPLA---------------------------PELRARQLELGAEHALLLD 174

  Fly   191 ANGDVFTWGNGLRGQLGLAELRVEETPQLLEALAGIKITQIAAGGWHSAAISAFGDLYTWGLNCS 255
            |.|.||:||.|..||||...|..|..|:|||||.|:.:.::|||||||..:|..||:|.||.|.|
Human   175 AAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQGLVMAEVAAGGWHSVCVSETGDIYIWGWNES 239

  Fly   256 GQL------------------------GLRVMKPGGVLK-EPTVF----PLPQLQDLPECACSQS 291
            |||                        |.:|.:.||... .|..|    |.|.|.|||
Human   240 GQLALPTRNLAEDGETVAREATELNEDGSQVKRTGGAEDGAPAPFIAVQPFPALLDLP------- 297

  Fly   292 GESNDDCAPLRVFAGSRHTLLIRRCGRLWVSGWCKHGQLGRQLQDLSYVDAFQALE-GITMNPTV 355
              ...|.  ::...|||||.::.|.|.|:..||.|:||||.  :|.:.:|..:.:| .:.....|
Human   298 --MGSDA--VKASCGSRHTAVVTRTGELYTWGWGKYGQLGH--EDTTSLDRPRRVEYFVDKQLQV 356

  Fly   356 DDVLCGPWSTLLH 368
            ..|.||||:|.::
Human   357 KAVTCGPWNTYVY 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6678	NP_650996.1	ATS1	175..>331	CDD:444065	73/184 (40%)
RCCD1	NP_291022.2	Interaction with KDM8. /evidence=ECO:0000269|PubMed:24981860	1..169		45/188 (24%)
		ATS1	<160..368	CDD:444065	84/220 (38%)
		RCC1 2	176..227		26/50 (52%)
		RCC1 3	229..317		28/98 (29%)
		RCC1 4	318..371		19/54 (35%)