Protein Alignment CG6678 and HERC1

DIOPT Version :9

• Sequence 1: NP_650996.1
• Gene: CG6678 / 42581
• FlyBaseID: FBgn0038917
• Length: 373
• Species: Drosophila melanogaster
• Sequence 2: XP_016878188.1
• Gene: HERC1 / 8925
• HGNCID: 4867
• Length: 4909
• Species: Homo sapiens
• Alignment Length: 438
• Identity: 101/438 - (23%)
• Similarity: 156/438 - (35%)
• Gaps: 133/438 - (30%)

  Fly     1 MPLLFTGFNAFGQHECVSGD-------VDCAAGFSE--------LNAPVSTQNQCTISIGWRYAA 50
            :|::.....|:.:...|.||       :.|.|..:.        .|.||...:|
Human  3905 LPMMLQEQYAYEKPHVVCGDQLVHSPYMQCLASLAVGLHLDQLLCNPPVPPHHQ----------- 3958

  Fly    51 LAFGRKLCLRGLLDDGPNECVTLEATGNIRALAAADSHCLVLLQSGQLYRVQPKLQAELV----- 110
                  .||.......|||...||........|.|.::.....:|..:..::|..:.|||
Human  3959 ------NCLPDPASWNPNEWAWLECFSTTIKAAEALTNGAQFPESFTVPDLEPVPEDELVFLMDN 4017

  Fly   111 ----------------------------AVRLEAAPR----SNSGTKRSIFGAAKAPSSPIIEHI 143
                                        .|.|..|.|    :.:|  |::...|.|||....:.:
Human  4018 SKWINGMDEQIMSWATSRPEDWHLGGKCDVYLWGAGRHGQLAEAG--RNVMVPAAAPSFSQAQQV 4080

  Fly   144 ACGSHINVAISSENCVYSIPSC---------------LHQFSE----RQFRVKQL--QCGHE-HA 186
            .||.:....|.:...|.   :|               ||..:.    :.|.|.||  .||.: |:
Human  4081 ICGQNCTFVIQANGTVL---ACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHS 4142

  Fly   187 VLLNANGDVFTWGNGLRGQLGLAELRVEETPQLLEALAGIKITQIAAGGWHSAAISAFGDLYTWG 251
            :.|..:|:||:||:|..|:||......:..|:.:|||.|.::.|::.|..|||.:::.|.|:|:|
Human  4143 MALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFG 4207

  Fly   252 LNCSGQLGLRVMKPGGVLKEPTVFPLPQLQDLPECACSQSGESNDDCAPLRVFAGSRHTLLIRRC 316
            ....|:|||     |....          :.|||...:..|....     :|..|..|||.:...
Human  4208 NGDYGRLGL-----GNTSN----------KKLPERVTALEGYQIG-----QVACGLNHTLAVSAD 4252

  Fly   317 GRL-WVSGWCKHGQLGRQLQDLSYVDAFQALEGIT--MNPTVDDVLCG 361
            |.: |..|...:|:||              |...|  .:|...|||||
Human  4253 GSMVWAFGDGDYGKLG--------------LGNSTAKSSPQKIDVLCG 4286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6678	NP_650996.1	ATS1	<78..371	CDD:227511	83/346 (24%)
		RCC1_2	176..205	CDD:290274	13/31 (42%)
		RCC1	192..241	CDD:278826	19/48 (40%)
		RCC1_2	228..257	CDD:290274	9/28 (32%)
HERC1	XP_016878188.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910