DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6678 and hectd3

DIOPT Version :9

Sequence 1:	NP_650996.1	Gene:	CG6678 / 42581	FlyBaseID:	FBgn0038917	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_001072497.1	Gene:	hectd3 / 779952	XenbaseID:	XB-GENE-5937967	Length:	845	Species:	Xenopus tropicalis

Alignment Length:	355	Identity:	75/355 - (21%)
Similarity:	111/355 - (31%)	Gaps:	135/355 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 EC---VSGDVDCAAGFSELNAPVS-------------------TQNQCTIS-------------- 43
            ||   ..|.:|...||.:..|.:|                   |.||...:
Frog   513 ECKFIAEGIIDQGGGFRDSLADISEELCPSSADIPVPLPFFVRTSNQGNGTGEAQDMYVPNPSCK 577

  Fly    44 -------IGWRYAALAFGRK---LCLRGLLDDGPNECVTLEATGN----IRALAAADSHCLVLLQ 94
                   ||....|...|::   |.|.||        |..:.||.    .:...|.||..:.||:
Frog   578 DLAKYEWIGQLMGAALRGKEFLVLALPGL--------VWKQLTGEEVSWSKDFPAVDSLLVKLLE 634

  Fly    95 SGQLYRVQP---KLQAELVAVRLEAAPRSNSGTKRSIFGAAKAPSSPIIEHIACGSHINVAISSE 156
            ..:|...:.   |...||              |..::....|     ::|.:..||:|:|.....
Frog   635 MMELMDEETFEFKFSGEL--------------TYTTVLSDQK-----MVELVPGGSNISVLYKDR 680

  Fly   157 -NCVYSIPSCLHQFSERQFRVKQLQCG----HEHAVLLNANGDVFTWGNGLRGQLGLAELRVEET 216
             ..:..:...  :..|.:.::..||.|    ...|||     |:.||..        .|.||...
Frog   681 VEFIRMVQKA--RLEESKEQIGALQAGLLKVVPQAVL-----DLLTWQE--------LEKRVCGD 730

  Fly   217 PQL-LEALAGIKITQIAAGGWHSAAISAFGDL--------YTWG-----LNCSGQLGLRVMKPGG 267
            |:: :|||.  |:|:             |||:        |.|.     .|......||.:....
Frog   731 PEITVEALK--KLTR-------------FGDIEQTDTRVQYFWEALNNFTNEDRSRFLRFVTGRS 780

  Fly   268 VLKEPT-VFP----LPQLQDLPECA-CSQS 291
            .|..|. ::|    |.....|||.: ||.|
Frog   781 RLPAPIYIYPDRSWLGTDDSLPESSTCSSS 810

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6678	NP_650996.1	ATS1	<78..371	CDD:227511	53/246 (22%)
		RCC1_2	176..205	CDD:290274	9/32 (28%)
		RCC1	192..241	CDD:278826	12/49 (24%)
		RCC1_2	228..257	CDD:290274	7/41 (17%)
hectd3	NP_001072497.1	APC10-HECTD3	222..355	CDD:176487
hectd3	NP_001072497.1	HECTc	512..837	CDD:421431	75/355 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010