Protein Alignment CG6678 and RPGR

DIOPT Version :10

• Sequence 1: NP_650996.1
• Gene: CG6678 / 42581
• FlyBaseID: FBgn0038917
• Length: 373
• Species: Drosophila melanogaster
• Sequence 2: NP_001030025.1
• Gene: RPGR / 6103
• HGNCID: 10295
• Length: 1152
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 82/339 - (24%)
• Similarity: 135/339 - (39%)
• Gaps: 77/339 - (22%)

  Fly    29 ELNAPVSTQNQCTI--SIGWRYAAL----AFGRKLCLRGLLDDGPNECVTLEATGNIRALAAADS 87
            |.:|.|:..|:..:  |..|....|    |..:..|::.|    ..|.|.|.|.|.        :
Human    45 EHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKAL----KPEKVKLAACGR--------N 97

  Fly    88 HCLVLLQSGQLYRVQPKLQAELVAVRLEAAPRSNSGTKRSIFGAAKAPSSPIIEHIACGSHINVA 152
            |.||..:.|.:|......:.:|   .|......|:....|.|     .|...|:.::.||:.:.|
Human    98 HTLVSTEGGNVYATGGNNEGQL---GLGDTEERNTFHVISFF-----TSEHKIKQLSAGSNTSAA 154

  Fly   153 ISSENCVYSIPSCLHQFSERQFRVKQ------------------LQCGHEHAVLLNANGDVFTWG 199
            ::.:..::    .....||.|..:|.                  :.||:.|:..:..:|:::.:|
Human   155 LTEDGRLF----MWGDNSEGQIGLKNVSNVCVPQQVTIGKPVSWISCGYYHSAFVTTDGELYVFG 215

  Fly   200 NGLRGQLGLAE--LRVEETPQLLEALAGIKITQIAAGGWHSAAISAFGDLYTWGLNCSGQLGLRV 262
            ....|:|||..  |....||||:..:.. |:.|:|.||.|:..::. ..:||:||...|||||
Human   216 EPENGKLGLPNQLLGNHRTPQLVSEIPE-KVIQVACGGEHTVVLTE-NAVYTFGLGQFGQLGL-- 276

  Fly   263 MKPGGVL---KEPTVFPLPQLQDLPECACSQSGESNDDCAPLRVFAGSRHTLLIRRCGRLWVSGW 324
               |..|   .||.|....:.|.:...:|                 |..||.||...|.::..|.
Human   277 ---GTFLFETSEPKVIENIRDQTISYISC-----------------GENHTALITDIGLMYTFGD 321

  Fly   325 CKHGQLGRQLQDLS 338
            .:||:||..|::.:
Human   322 GRHGKLGLGLENFT 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6678	NP_650996.1	ATS1	175..>331	CDD:444065	46/178 (26%)
RPGR	NP_001030025.1	ATS1	38..360	CDD:444065	82/339 (24%)