DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6678 and LOC567670

DIOPT Version :9

Sequence 1:	NP_650996.1	Gene:	CG6678 / 42581	FlyBaseID:	FBgn0038917	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	XP_021324683.1	Gene:	LOC567670 / 567670	-ID:	-	Length:	4796	Species:	Danio rerio

Alignment Length:	374	Identity:	93/374 - (24%)
Similarity:	150/374 - (40%)	Gaps:	77/374 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 QHECVSGDVDCAAGFSELNAPV---STQNQCTISIGWRYAALAFGRKLCLRGLLDDGPNECVTLE 74
            ||..|.|:        .:|..|   .....|::|    :.||....::|...      :.|:...
Zfish   309 QHTAVRGE--------SVNTQVLKKDADGLCSLS----HVALCLFEEICTLA------SNCLCSC 355

  Fly    75 ATGNIRALAAADSHCLVL---------LQSGQLYRV-QPKL-QAELVAVRLEAAPRSNSGTKRSI 128
            :.|:..:..:.:...:|.         |..|.|.:: |||| |....|..:||........  |.
Zfish   356 SAGSSSSSGSENDTVMVYVWGSNSSHQLAEGTLEKILQPKLAQGFSDAQMIEAGQYCTFSV--SA 418

  Fly   129 FGAAKAPSSPIIEHIAC--GSHINVAISSENCVYSIPSCLHQFSERQFRVKQLQCGHE-HAVLLN 190
            .||.|          ||  ||:..:.:...| ..|:|..|.....|..|......|.: |.:.:.
Zfish   419 DGAVK----------ACGKGSYGRLGLGDSN-NQSMPKKLVLEPPRTMRKVSSSKGSDGHTLAVT 472

  Fly   191 ANGDVFTWGNGLRGQLGLAELRVEETPQLLEA-LAGIKITQIAAGGWHSAAISAFGDLYTWGLNC 254
            |.|:||:||:|..|:||......::.|::::. |.|..:..::||..||||::..|:|||||...
Zfish   473 AEGEVFSWGDGDYGKLGHGNSATQKYPKIIQGPLLGKVVVCVSAGYRHSAAVTNDGELYTWGEGD 537

  Fly   255 SGQLGLRVMKPGGVLKEPTVFPLPQLQDLPECACSQSGESNDDCAPLRVFAGSRHTLLIRRCGRL 319
            .|:||........|   ||:  :..:..:.:.||                 ||.||:.:.:.||:
Zfish   538 FGRLGHSDSHSRNV---PTL--VKDISGVGQVAC-----------------GSSHTIAVAQDGRI 580

  Fly   320 -WVSGWCKHGQLGRQLQDLSY-VDAFQALEGITMNPTVDDVLCGPWSTL 366
             |..|...:|:||....:..| ....:||.|.    .:..|..|..|:|
Zfish   581 VWSFGGGDNGKLGHGDTNRVYRPKVIEALHGF----IIRKVCAGSQSSL 625

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6678	NP_650996.1	ATS1	<78..371	CDD:227511	80/306 (26%)
		RCC1_2	176..205	CDD:290274	9/29 (31%)
		RCC1	192..241	CDD:278826	17/49 (35%)
		RCC1_2	228..257	CDD:290274	12/28 (43%)
LOC567670	XP_021324683.1	RCC1	371..724	CDD:332518	80/294 (27%)
		SPRY_HERC1	1975..2131	CDD:293939
		UBA_HERC1	2682..2725	CDD:270584
		WD40	3351..3707	CDD:330360
		WD40 repeat	3362..3400	CDD:293791
		WD40 repeat	3420..3451	CDD:293791
		WD40 repeat	3458..3512	CDD:293791
		WD40 repeat	3520..3557	CDD:293791
		WD40 repeat	3563..3587	CDD:293791
		WD40 repeat	3606..3653	CDD:293791
		WD40 repeat	3682..3718	CDD:293791
		RCC1	3869..4282	CDD:332518
		HECTc	4408..4776	CDD:238033
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010