DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6678 and rcc1

DIOPT Version :9

Sequence 1:	NP_650996.1	Gene:	CG6678 / 42581	FlyBaseID:	FBgn0038917	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_998343.1	Gene:	rcc1 / 406457	ZFINID:	ZDB-GENE-040426-2216	Length:	418	Species:	Danio rerio

Alignment Length:	204	Identity:	57/204 - (27%)
Similarity:	95/204 - (46%)	Gaps:	37/204 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   176 VKQLQCGHEHAVLLNANGDVFTWGNGLRGQLG--LAELRVEETPQLLEALAGIKITQIAAGGWHS 238
            :.|...|..|.|.|:..|:|:|:|....|.||  .:|...|..|..::  .|.||.|::||..||
Zfish    69 IVQAVAGGMHTVCLSDTGNVYTFGCNDEGALGRDTSEEGSETVPAKVD--LGEKIIQVSAGDSHS 131

  Fly   239 AAISAFGDLYTWG--LNCSGQLGLRVMKPGGVLKEPTVFPLPQLQDLPECACSQSGESNDDCAPL 301
            ||::..|.:|.||  .:.:|.:||  ::|   :|:.|| |:....|.|               .:
Zfish   132 AALTEDGGVYVWGSFRDNNGVIGL--LEP---MKKCTV-PVKVPIDKP---------------VV 175

  Fly   302 RVFAGSRHTLLIRRCGRLWVSGWCKHGQLGRQLQDLSYVDAFQAL------EGITMNP----TVD 356
            ::.:|:.|.:::...|.|:.||..:.|||||..:..:.....:.|      :.:.:.|    ...
Zfish   176 KIVSGNDHLVMLTAHGELYTSGCGEQGQLGRVAEHFANRGGRKGLMRLLEPQMVIIKPRGKVVFT 240

  Fly   357 DVLCGPWST 365
            ||.||.:.|
Zfish   241 DVFCGAYFT 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6678	NP_650996.1	ATS1	<78..371	CDD:227511	57/204 (28%)
		RCC1_2	176..205	CDD:290274	9/28 (32%)
		RCC1	192..241	CDD:278826	19/50 (38%)
		RCC1_2	228..257	CDD:290274	12/30 (40%)
rcc1	NP_998343.1	ATS1	3..415	CDD:227511	57/204 (28%)
		RCC1	34..82	CDD:278826	4/12 (33%)
		RCC1	86..134	CDD:278826	19/49 (39%)
		RCC1	137..187	CDD:278826	16/70 (23%)
		RCC1	191..252	CDD:278826	16/59 (27%)
		RCC1	255..306	CDD:278826
		RCC1	309..357	CDD:278826
		RCC1	361..411	CDD:278826
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910