DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6678 and Herc6

DIOPT Version :9

Sequence 1:	NP_650996.1	Gene:	CG6678 / 42581	FlyBaseID:	FBgn0038917	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	XP_008761185.1	Gene:	Herc6 / 362376	RGDID:	1561739	Length:	1027	Species:	Rattus norvegicus

Alignment Length:	333	Identity:	89/333 - (26%)
Similarity:	148/333 - (44%)	Gaps:	76/333 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 LEATGNIRALAAA--DSHCLVLLQSGQLYRVQPKLQAELVAVRLEAAPRSNSGTKRSIFGAAKAP 135
            |||...::.|.||  :.|.|:|..:.::|......:.:|       ..:|...|||.  ...:|.
  Rat    15 LEAGTGLKLLKAASGERHSLLLFSNHRVYSCGDNSRGQL-------GQKSPQSTKRP--EPIQAL 70

  Fly   136 SSPIIEHIACGSHINVAISSENCVYS-------------------IPSCLHQFSERQFRVKQLQC 181
            |:..|:.::||...:||:..:..|::                   :|:.::..:  ..::.|:.|
  Rat    71 STVHIDLVSCGKEHSVAVCHQGRVFTWGAGSEGQLGIGESKEISFMPTKINSLA--GIKIIQVSC 133

  Fly   182 GHEHAVLLNANGDVFTWGNGLRGQLGLA-ELRVEETPQLLEALAGIKITQIAAGGWHSAAISAFG 245
            ||.|::.|:.:|.||:||:..:|||||. .|..:.:||.:::|.||.:.|:||||.||.|:|..|
  Rat   134 GHYHSLALSEDGQVFSWGSNRQGQLGLGNNLCSQASPQKVKSLEGIPLAQVAAGGTHSFALSLMG 198

  Fly   246 DLYTWGLNCSGQLGL-------RVMKPG--GVLKEPTVFPLPQLQDLPECACSQSGESNDDCAPL 301
            ..:.||.|.||||.|       ::.||.  |.||...|                          :
  Rat   199 TSFGWGNNRSGQLALSGNSAKEQIYKPHSIGALKTLNV--------------------------V 237

  Fly   302 RVFAGSRHTLLIRRCGRLWVSGWCKHGQLGRQLQ--DLSYVDAFQALEGITMNPTVDDVLCGPWS 364
            .:..|..||.::...|:::..|    |....|||  ..|.....|.:|||  ...|..:.||.:.
  Rat   238 YISCGYEHTSVLTEDGQVFTFG----GSSSEQLQHSPRSGRGGPQLIEGI--GGHVSQIECGSYH 296

  Fly   365 TLLHLKCT 372
            |:.::..|
  Rat   297 TIAYVYTT 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6678	NP_650996.1	ATS1	<78..371	CDD:227511	85/325 (26%)
		RCC1_2	176..205	CDD:290274	11/28 (39%)
		RCC1	192..241	CDD:278826	23/49 (47%)
		RCC1_2	228..257	CDD:290274	14/28 (50%)
Herc6	XP_008761185.1	RCC1	39..88	CDD:278826	12/57 (21%)
		RCC1	92..141	CDD:278826	7/50 (14%)
		RCC1	144..194	CDD:278826	23/49 (47%)
		RCC1_2	182..210	CDD:290274	14/27 (52%)
		RCC1_2	236..265	CDD:290274	7/58 (12%)
		RCC1	252..299	CDD:278826	15/52 (29%)
		HECTc	682..1023	CDD:238033
		HECTc	706..1023	CDD:214523
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920