DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6678 and Rcc1l

DIOPT Version :9

Sequence 1:	NP_650996.1	Gene:	CG6678 / 42581	FlyBaseID:	FBgn0038917	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_001101802.1	Gene:	Rcc1l / 360796	RGDID:	1307558	Length:	461	Species:	Rattus norvegicus

Alignment Length:	227	Identity:	62/227 - (27%)
Similarity:	100/227 - (44%)	Gaps:	34/227 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 HIACGSHINVAISSENCVYSIPSCLHQFSERQFRVKQLQCGHEHAVLLNANGDVFTWGNGLRGQL 206
            |..||..:     .|:.|||....:|:..:.:.:|.|:.||.:|::.|...|:|::.|.|..||.
  Rat   200 HGQCGRKV-----VEDEVYSESHKVHRMQDFEGQVVQVVCGQDHSLFLTDKGEVYSCGWGADGQT 259

  Fly   207 GLAELRVEETPQLLEA-LAGIKITQIAAGGWHSAAISAFGDLYTWGLNCSGQLGLRVMKPGGVLK 270
            ||....:..||..|.. |||:.:.|:|..|....|:||.|.::.||  .|..|.|..:.....:.
  Rat   260 GLGHYNITSTPSKLGGDLAGVTVVQVATYGDCCLALSADGGVFGWG--NSEYLQLASVTDSTQVN 322

  Fly   271 EPTVFPLPQLQDLPECACSQSGESNDDCAPLRVFAGSRHTLLIRRCGRLWVSGWCKHGQLGR--Q 333
            .|...|...:..:.:.||..:|     ||            ::...|.::|.|   :|.||:  .
  Rat   323 VPRCLPFSGVGKVKQVACGGTG-----CA------------ILNEEGHVFVWG---YGILGKGPN 367

  Fly   334 LQDLSYVDAF-QALEGIT-MNP--TVDDVLCG 361
            |.:.:..:.. ..|.|:| .||  .|..:.||
  Rat   368 LSETALPEMIPPTLFGLTEFNPEVKVSQIRCG 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6678	NP_650996.1	ATS1	<78..371	CDD:227511	62/227 (27%)
		RCC1_2	176..205	CDD:290274	10/28 (36%)
		RCC1	192..241	CDD:278826	17/49 (35%)
		RCC1_2	228..257	CDD:290274	10/28 (36%)
Rcc1l	NP_001101802.1	RCC1	127..186	CDD:278826
		RCC1_2	173..202	CDD:290274	1/1 (100%)
		RCC1	192..242	CDD:278826	13/46 (28%)
		RCC1_2	229..258	CDD:290274	10/28 (36%)
		RCC1	245..295	CDD:278826	17/49 (35%)
		RCC1	298..348	CDD:278826	13/68 (19%)
		RCC1_2	393..422	CDD:290274	3/7 (43%)
		RCC1	409..452	CDD:278826
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910