DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6678 and CG3862

DIOPT Version :9

Sequence 1:	NP_650996.1	Gene:	CG6678 / 42581	FlyBaseID:	FBgn0038917	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster

Alignment Length:	379	Identity:	81/379 - (21%)
Similarity:	133/379 - (35%)	Gaps:	126/379 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 STQNQCT-ISIGWRYAALAFGRKLCLRGLLDDG---------------------PNECVTLEA-- 75
            |..|:.| ::.|:.:...|..|        |||                     ||:...|:.
  Fly    83 SNNNEITDVAAGYGFTVYAVNR--------DDGETLFGSGLNTDSQLGFQVKGNPNDPANLDVII 139

  Fly    76 ----------------TGNIRALAAADSHCLVLLQSGQLYRVQPKLQAELVAVRLEAAPRSNSGT 124
                            ...:::::|..:|.:||.|:|.::.:               ...|....
  Fly   140 YPTAIKLPRVQGETDEDMRVKSMSAGRAHLVVLTQNGTIFTL---------------GNNSYGQC 189

  Fly   125 KRSIFGAAKAPSSPIIEHIA---------------CGSHINVAISSENCVYSIPSC--------- 165
            .|||....:...|.:|..|:               ||...::.::.:..:|   :|
  Fly   190 GRSIIEEERYSKSALIHRISQEDICGKEDEVVQVECGQDHSMFLTKKGRIY---TCGWGADGQTG 251

  Fly   166 ---LHQFSE--------RQFRVKQLQCGHEHAVLLNANGDVFTWGNGLRGQLG---LAELRVEET 216
               .|...:        .:.::.:|.|..:..:.||..||.|.|||...|||.   |||.:: ..
  Fly   252 QGNYHTAGQITLIGGDVEKEKIVRLSCSSDCVLALNEAGDAFGWGNSEYGQLDDSELAETQI-NI 315

  Fly   217 PQLLEALAGI-KITQIAAGGWHSAAISAFGDLYTWGLNCSGQLGLRVMKPGGVLKEPTVFP---L 277
            |:.|:....| ||..:||||....|::..|.:||||.   |.||.      |...|.|..|   |
  Fly   316 PRALKLTKSIGKIKDVAAGGSFCMALNDQGLVYTWGF---GILGF------GPFVEQTSKPQHLL 371

  Fly   278 PQLQDLPECACSQSGESNDDCAPLRVFAGSRHTLLIRRCGRLWVSGWCKHGQLG 331
            |.|       ..::..||:... :.:..|..|...:...|.|::.|..:.|.||
  Fly   372 PPL-------FGRNDFSNETTV-VSIGCGVFHMGAVNSDGDLFMWGKNRFGHLG 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6678	NP_650996.1	ATS1	<78..371	CDD:227511	69/296 (23%)
		RCC1_2	176..205	CDD:290274	10/28 (36%)
		RCC1	192..241	CDD:278826	21/52 (40%)
		RCC1_2	228..257	CDD:290274	11/28 (39%)
CG3862	NP_608550.1	RCC1	43..99	CDD:278826	4/15 (27%)
		RCC1_2	159..188	CDD:290274	7/43 (16%)
		RCC1	175..233	CDD:278826	10/72 (14%)
		RCC1_2	220..249	CDD:290274	4/31 (13%)
		RCC1	236..286	CDD:278826	5/52 (10%)
		RCC1	290..341	CDD:278826	21/51 (41%)
		RCC1	345..395	CDD:278826	18/66 (27%)
		RCC1_2	386..414	CDD:290274	5/28 (18%)
		RCC1	402..449	CDD:278826	6/16 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442602
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840