DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6678 and Herc4

DIOPT Version :9

Sequence 1:NP_650996.1 Gene:CG6678 / 42581 FlyBaseID:FBgn0038917 Length:373 Species:Drosophila melanogaster
Sequence 2:NP_001012074.1 Gene:Herc4 / 309758 RGDID:1310971 Length:1057 Species:Rattus norvegicus


Alignment Length:335 Identity:82/335 - (24%)
Similarity:128/335 - (38%) Gaps:116/335 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    62 LLDDG---------------------PNECVTLEATGNIRALAAADSHCLVLLQSGQLYRVQPKL 105
            :||||                     |.:.|.|:|. ||.|::..::|.|.|...||:|      
  Rat    49 VLDDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDAQ-NIVAVSCGEAHTLALNDKGQVY------ 106

  Fly   106 QAELVAVRLEAAPRSNSGTKRSIFGAAKAPSSPIIEHIACGSHINVAISSENCVYSIPSCLHQFS 170
                       |...:|..:..:.|                        ||.|: .:|..:...|
  Rat   107 -----------AWGLDSDGQLGLQG------------------------SEECI-RVPRNIKSLS 135

  Fly   171 ERQFRVKQLQCGHEHAVLLNANGDVFTWGNGLRGQLGLA-ELRVEETPQLLEALAGIKITQIAAG 234
            :.|  :.|:.||:.|::.|:...:||.||....|||||. |.:.:.:|||:::|.||...|:|||
  Rat   136 DIQ--IVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGIECQKQTSPQLIKSLLGIPFMQVAAG 198

  Fly   235 GWHSAAISAFGDLYTWGLNCSGQLGLRVMKPGGVLKEPTVFPLPQLQDLPECACSQSGESNDDCA 299
            |.||..::..|.::.||.|..|||||                               .:.||...
  Rat   199 GAHSFVLTLSGAIFGWGRNKFGQLGL-------------------------------NDENDRYV 232

  Fly   300 P-----LR------VFAGSRHTLLIRRCGRLWVSGWCKHGQLGRQ--LQDLSYVDAFQALEGITM 351
            |     ||      :..|..||..:.:.|.::..|...:||||..  ..:::....|:.:..|  
  Rat   233 PNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSI-- 295

  Fly   352 NPTVDDVLCG 361
               |..:.||
  Rat   296 ---VTQIACG 302

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6678NP_650996.1 ATS1 <78..371 CDD:227511 74/298 (25%)
RCC1_2 176..205 CDD:290274 9/28 (32%)
RCC1 192..241 CDD:278826 23/49 (47%)
RCC1_2 228..257 CDD:290274 11/28 (39%)
Herc4NP_001012074.1 RCC1 1 1..51 0/1 (0%)
RCC1 3..49 CDD:278826 82/335 (24%)
RCC1 2 52..101 12/49 (24%)
RCC1 52..99 CDD:278826 11/47 (23%)
RCC1 3 102..154 17/95 (18%)
RCC1 102..152 CDD:278826 16/93 (17%)
RCC1 4 156..207 23/50 (46%)
RCC1 157..205 CDD:278826 23/47 (49%)
RCC1 5 208..259 17/81 (21%)
RCC1 208..257 CDD:278826 17/79 (22%)
RCC1 260..308 CDD:278826 11/48 (23%)
RCC1 6 261..311 11/47 (23%)
RCC1 7 313..366
RCC1 313..>343 CDD:278826
HECTc 709..1055 CDD:238033
HECTc 735..1054 CDD:214523
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1062377at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.920

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