DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6678 and Nek9

DIOPT Version :9

Sequence 1:	NP_650996.1	Gene:	CG6678 / 42581	FlyBaseID:	FBgn0038917	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_001100217.2	Gene:	Nek9 / 299204	RGDID:	1307187	Length:	976	Species:	Rattus norvegicus

Alignment Length:	431	Identity:	91/431 - (21%)
Similarity:	142/431 - (32%)	Gaps:	123/431 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 LNAPVSTQNQCTISIGWRYAALAFGRKLCLRGLLDDGPNECVTLEATGNIRALAAADSHCLVLLQ 94
            ||||.......|::........:...::.:.|.....|.:...:::..:.|.:.|.::|..|:..
  Rat   321 LNAPTKRPRSSTVTEAPIAVVTSRTSEVYVWGGGKSTPQKLDVIKSGCSARQVCAGNTHFAVVTV 385

  Fly    95 SGQLY---RVQ--PKLQAELVAVRLEAAPRSNSGTKRSIFGAAKAP------SSPIIEHIACGSH 148
            ..:||   .:|  .||..:|           ..|.|.|.    :.|      ....|..::||..
  Rat   386 EKELYTWVNMQGGTKLHGQL-----------GHGDKASY----RQPKHVEKLQGKAIHQVSCGDD 435

  Fly   149 INVAISSENCVYSI---------------PSCLHQFSERQF---RVKQLQCGHEHAVLLNANGDV 195
            ..|.::.|..:|:.               |..|.......|   .|:|:.||..|.|:|..|.:|
  Rat   436 FTVCVTDEGQLYAFGSDYYGCMGVDKVSGPEVLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEV 500

  Fly   196 FTWGNGLRGQLGLAELRVEETPQLLEALAGIKITQIAAGGWHSAAISAFGDLYTWGLNCSGQLGL 260
            ::||.|..|:|||.......|||.::....:.|..:..|...:..::..|.:...|||...:|||
  Rat   501 YSWGCGEYGRLGLDSEEDYYTPQRVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGL 565

  Fly   261 RVMKPGGVLKE-------PTVFPLPQLQDLPECACSQSGESNDDCAPLRVFA-GSRHTLLIRRCG 317
            .....|.:..|       .|.|.|.:.....:               :|..| |..||..|...|
  Rat   566 NQCMSGIINHEAYHEVPYTTSFTLAKQLSFYK---------------IRTIAPGKTHTAAIDERG 615

  Fly   318 RLWVSGWCKHGQL-------------------GRQLQDLSYVDAFQALE---------------G 348
            ||...|..|.|||                   |:|:..:|..|.|....               .
  Rat   616 RLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDNHIFAWGNGGNGR 680

  Fly   349 ITMNPT----------------------VDDVLCGPWSTLL 367
            :.|.||                      |.|:.|..|.|:|
  Rat   681 LAMTPTERPHGSDICTSWPRPIFGSLHHVPDLSCRGWHTIL 721

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6678	NP_650996.1	ATS1	<78..371	CDD:227511	84/383 (22%)
		RCC1_2	176..205	CDD:290274	12/28 (43%)
		RCC1	192..241	CDD:278826	14/48 (29%)
		RCC1_2	228..257	CDD:290274	6/28 (21%)
Nek9	NP_001100217.2	STKc_Nek9	50..297	CDD:270860
Nek9	NP_001100217.2	ATS1	344..687	CDD:227511	79/372 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010