DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG6678 and SERGEF

DIOPT Version :9

Sequence 1:NP_650996.1 Gene:CG6678 / 42581 FlyBaseID:FBgn0038917 Length:373 Species:Drosophila melanogaster
Sequence 2:NP_036271.1 Gene:SERGEF / 26297 HGNCID:17499 Length:458 Species:Homo sapiens


Alignment Length:354 Identity:84/354 - (23%)
Similarity:124/354 - (35%) Gaps:91/354 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    61 GLLDDGPNECVTLEATGN-------IRALAAADSHCLVLLQSGQLYRVQPKLQAELVAVRLEAAP 118
            |.|..|..|.|.|....|       :|.:.....|..|:...|.|:........:|.....|..|
Human    26 GQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEDIP 90

  Fly   119 RSNSGTKRSIFGAAKAPSSPIIEHIACGSHINVAISSENCVYS-------------------IPS 164
            ...  ..:|:||..       |:.:|||....:.::....|.|                   :|.
Human    91 YFT--PCKSLFGCP-------IQQVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQ 146

  Fly   165 CLHQFSERQFRVKQLQCGHEHAVLLNANGDVFTWGNGLR--------GQLGLAELRVEETPQLLE 221
            .:....|   :|..:..|..|||...|:|.||.||.||.        ||. |......:.|..:.
Human   147 AIELHKE---KVVCIAAGLRHAVAATASGIVFQWGTGLASCGRRLCPGQT-LPLFFTAKEPSRVT 207

  Fly   222 ALAGIKITQIAAGGWHSAAISAFGDLYTWGLNCSGQLGLRVMKPGGVLKEPTVFPLPQLQDLPEC 286
            .|...|...:.||..|||:::..|::|.||.|..|||.          .|....|:||   ..|.
Human   208 GLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLA----------NEAAFLPVPQ---KIEA 259

  Fly   287 ACSQSGESNDDCAPLRVFAGSRHTLLIRRCGRLWVSGWCKHGQLGRQLQ-----DLSYVDAF--- 343
            .|.|:.:..      .:::|..|.:.....|:::..|...:|||||:|:     .|...|:|   
Human   260 HCFQNEKVT------AIWSGWTHLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPC 318

  Fly   344 -----------QALEGITMNPTVDDVLCG 361
                       ..|.|.|      :|.||
Human   319 SRPPNSMPSSPHCLTGAT------EVSCG 341

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6678NP_650996.1 ATS1 <78..371 CDD:227511 78/337 (23%)
RCC1_2 176..205 CDD:290274 13/36 (36%)
RCC1 192..241 CDD:278826 18/56 (32%)
RCC1_2 228..257 CDD:290274 10/28 (36%)
SERGEFNP_036271.1 RCC1 1 15..67 10/40 (25%)
RCC1 23..64 CDD:278826 9/37 (24%)
RCC1 2 68..119 12/59 (20%)
RCC1 68..116 CDD:278826 12/56 (21%)
RCC1_2 103..132 CDD:290274 6/28 (21%)
RCC1 119..167 CDD:278826 8/50 (16%)
RCC1 3 120..171 9/53 (17%)
RCC1 4 172..230 18/58 (31%)
RCC1_2 219..243 CDD:290274 10/23 (43%)
RCC1 5 231..283 17/70 (24%)
RCC1 231..279 CDD:278826 17/66 (26%)
RCC1 6 284..351 17/64 (27%)
RCC1 284..348 CDD:278826 17/64 (27%)
RCC1 351..399 CDD:278826
RCC1 7 352..402
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 420..458
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5184
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1062377at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.910

Return to query results.
Submit another query.