DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6678 and Nek9

DIOPT Version :9

Sequence 1:NP_650996.1 Gene:CG6678 / 42581 FlyBaseID:FBgn0038917 Length:373 Species:Drosophila melanogaster
Sequence 2:NP_660120.2 Gene:Nek9 / 217718 MGIID:2387995 Length:984 Species:Mus musculus


Alignment Length:431 Identity:91/431 - (21%)
Similarity:142/431 - (32%) Gaps:123/431 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 LNAPVSTQNQCTISIGWRYAALAFGRKLCLRGLLDDGPNECVTLEATGNIRALAAADSHCLVLLQ 94
            ||||.......|::........:...::.:.|.....|.:...:::..:.|.:.|.::|..|:..
Mouse   322 LNAPTKRPRSSTVTEAPIAVVTSRTSEVYVWGGGKSTPQKLDVIKSGCSARQVCAGNTHFAVVTV 386

  Fly    95 SGQLY---RVQ--PKLQAELVAVRLEAAPRSNSGTKRSIFGAAKAP------SSPIIEHIACGSH 148
            ..:||   .:|  .||..:|           ..|.|.|.    :.|      ....|..::||..
Mouse   387 EKELYTWVNMQGGTKLHGQL-----------GHGDKASY----RQPKHVEKLQGKAIHQVSCGDD 436

  Fly   149 INVAISSENCVYSI---------------PSCLHQFSERQF---RVKQLQCGHEHAVLLNANGDV 195
            ..|.::.|..:|:.               |..|.......|   .|:|:.||..|.|:|..|.:|
Mouse   437 FTVCVTDEGQLYAFGSDYYGCMGVDKVSGPEVLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEV 501

  Fly   196 FTWGNGLRGQLGLAELRVEETPQLLEALAGIKITQIAAGGWHSAAISAFGDLYTWGLNCSGQLGL 260
            ::||.|..|:|||.......|||.::....:.|..:..|...:..::..|.:...|||...:|||
Mouse   502 YSWGCGEYGRLGLDSEEDYYTPQRVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGL 566

  Fly   261 RVMKPGGVLKE-------PTVFPLPQLQDLPECACSQSGESNDDCAPLRVFA-GSRHTLLIRRCG 317
            .....|.:..|       .|.|.|.:.....:               :|..| |..||..|...|
Mouse   567 NQCMSGIINHEAYHEVPYTTSFTLAKQLSFYK---------------IRTIAPGKTHTAAIDERG 616

  Fly   318 RLWVSGWCKHGQL-------------------GRQLQDLSYVDAFQALE---------------G 348
            ||...|..|.|||                   |:|:..:|..|.|....               .
Mouse   617 RLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDNHIFAWGNGGNGR 681

  Fly   349 ITMNPT----------------------VDDVLCGPWSTLL 367
            :.|.||                      |.|:.|..|.|:|
Mouse   682 LAMTPTERPHGSDICTSWPRPIFGSLHHVPDLSCRGWHTIL 722

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6678NP_650996.1 ATS1 <78..371 CDD:227511 84/383 (22%)
RCC1_2 176..205 CDD:290274 12/28 (43%)
RCC1 192..241 CDD:278826 14/48 (29%)
RCC1_2 228..257 CDD:290274 6/28 (21%)
Nek9NP_660120.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 14..43
STKc_Nek9 51..296 CDD:270860
S_TKc 52..296 CDD:214567
RCC1 1 388..444 14/70 (20%)
RCC1 389..441 CDD:278826 14/66 (21%)
RCC1 444..495 CDD:278826 11/50 (22%)
RCC1 2 445..498 11/52 (21%)
RCC1 3 499..550 13/50 (26%)
RCC1 500..547 CDD:278826 13/46 (28%)
RCC1 4 551..615 18/78 (23%)
RCC1 5 616..668 13/51 (25%)
RCC1 616..664 CDD:278826 13/47 (28%)
RCC1 6 669..726 9/54 (17%)
Interaction with NEK6. /evidence=ECO:0000250 732..896
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 744..790
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 940..984
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5184
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1062377at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.910

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