DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6678 and Rpgr

DIOPT Version :9

Sequence 1:	NP_650996.1	Gene:	CG6678 / 42581	FlyBaseID:	FBgn0038917	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_001171421.1	Gene:	Rpgr / 19893	MGIID:	1344037	Length:	1039	Species:	Mus musculus

Alignment Length:	332	Identity:	81/332 - (24%)
Similarity:	126/332 - (37%)	Gaps:	66/332 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 LAAADSHCLVLLQSGQLYRVQPKLQAELVAVRLEAAPRSNSGTKRSIF--GAAKAPSSPIIEHIA 144
            |:..|.|..::..:.:||........:|           ..|:|.:|.  ...||.....::..|
Mouse    78 LSCGDEHTAIVTGNNKLYMFGSNNWGQL-----------GLGSKAAIIKPTCIKALKPEKVKLAA 131

  Fly   145 CGSHINVAISSENCVYSI---------------PSCLHQ--FSERQFRVKQLQCGHEHAVLLNAN 192
            ||.:..:..:....||:.               ....||  |......:|||..|...:..|..:
Mouse   132 CGRNHTLVSTDTGGVYAAGGNNEGQLGLGDTDDRDTFHQIVFFTPADTIKQLSAGANTSAALTED 196

  Fly   193 GDVFTWGNGLRGQLGLAELRVEETPQLLEALAGIKITQIAAGGWHSAAISAFGDLYTWGLNCSGQ 257
            |.:|.||:...||:||.:......|.  |...|..|:.|:.|.:|||.::..|:|||:|...:|:
Mouse   197 GKLFMWGDNSEGQIGLEDKSNVCIPH--EVTVGKPISWISCGYYHSAFVTMDGELYTFGEPENGK 259

  Fly   258 LGL-------------------RVMK---PGG---VLKEPTV--FPLPQLQDLP------ECACS 289
            |||                   ||::   .||   ||.|..|  |.|.|...|.      |.:..
Mouse   260 LGLPNELLMNHRSPQRVLGIPERVIQVACGGGHTVVLTEKVVYAFGLGQFGQLGLGTFLFETSEP 324

  Fly   290 QSGESNDDCAPLRVFAGSRHTLLIRRCGRLWVSGWCKHGQLGRQLQDLSYVDAFQALEGITMNPT 354
            :..|...|.....:..|..||.|:...|.|:..|..:||:||..:::.:. ..|..|....:...
Mouse   325 KIIERIKDQKICHISCGENHTALMTELGLLYTFGDGRHGKLGLGMENFTN-QFFPTLCSNFLRFA 388

  Fly   355 VDDVLCG 361
            |..:.||
Mouse   389 VQLIACG 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6678	NP_650996.1	ATS1	<78..371	CDD:227511	81/332 (24%)
		RCC1_2	176..205	CDD:290274	9/28 (32%)
		RCC1	192..241	CDD:278826	17/48 (35%)
		RCC1_2	228..257	CDD:290274	11/28 (39%)
Rpgr	NP_001171421.1	RCC1_2	78..104	CDD:290274	5/25 (20%)
		RCC1	93..139	CDD:278826	11/56 (20%)
		RCC1	144..193	CDD:278826	9/48 (19%)
		RCC1_2	180..209	CDD:290274	9/28 (32%)
		RCC1	196..243	CDD:278826	17/48 (35%)
		RCC1	246..296	CDD:278826	13/49 (27%)
		RCC1	301..348	CDD:278826	11/46 (24%)
		RCC1	352..398	CDD:278826	12/45 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910