DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6678 and Ibtk

DIOPT Version :9

Sequence 1:NP_650996.1 Gene:CG6678 / 42581 FlyBaseID:FBgn0038917 Length:373 Species:Drosophila melanogaster
Sequence 2:NP_001074751.1 Gene:Ibtk / 108837 MGIID:1918677 Length:1352 Species:Mus musculus


Alignment Length:256 Identity:73/256 - (28%)
Similarity:112/256 - (43%) Gaps:54/256 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   146 GSHINVAI--SSENCVYSIPSCLHQFSERQFRVKQLQCGHEHAVLLNANGDVFTWGNGLRGQLGL 208
            |.:.|..:  .|:|..:. |..|..||.....|||:.....|:|.|:..|.|:|.|:|..|:||.
Mouse   148 GDNTNFTLGHGSQNSKHH-PELLDLFSRSGVYVKQVVLCKFHSVFLSQKGQVYTCGHGRGGRLGH 211

  Fly   209 AELRVEETPQLLEALAGIKITQIAAGGWHSAAISAFGDLYTWGLNCSGQLGLRVMKPGGVLKEPT 273
            .:.:....|:|:|.|:|...:|:||...|:..::..|.:||:|||...||        |::..|.
Mouse   212 GDEQTCLVPRLVEGLSGHNCSQVAAAKDHTVVLTDDGCVYTFGLNMFHQL--------GIIPPPA 268

  Fly   274 VFPLP-QLQDLPECACSQSGESNDDCAPLRVFAGSRHTLLIRR--CGRLWVSGWCKHGQLG---- 331
            ...:| |:|     |....|.:     .:.|.||..||:|..|  ...|.::|    ||||    
Mouse   269 SCNVPRQIQ-----AKYLKGRT-----IIGVAAGRFHTVLWTREAVYTLGLNG----GQLGHLLD 319

  Fly   332 ----------RQLQDLSYVDAFQAL----EGITMNPT-------VDDVLCGPWST-LLHLK 370
                      ||:..|.:.|...:|    :|.|:..|       :.|..|...:| .|:||
Mouse   320 PNGEKCVTTPRQVSALHHKDIAVSLVAASDGATVCVTTRGDIYLLADYQCKKMATKQLNLK 380

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6678NP_650996.1 ATS1 <78..371 CDD:227511 73/256 (29%)
RCC1_2 176..205 CDD:290274 11/28 (39%)
RCC1 192..241 CDD:278826 17/48 (35%)
RCC1_2 228..257 CDD:290274 10/28 (36%)
IbtkNP_001074751.1 Ank_2 25..116 CDD:289560
ANK <47..135 CDD:238125
ANK repeat 51..82 CDD:293786
ANK 1 51..80
ANK repeat 84..116 CDD:293786
ANK 2 85..114
RCC1 1 141..194 14/46 (30%)
RCC1 143..192 CDD:278826 13/44 (30%)
RCC1 2 195..246 17/50 (34%)
RCC1_2 232..260 CDD:290274 10/27 (37%)
RCC1 247..299 CDD:278826 20/69 (29%)
RCC1 3 248..301 21/70 (30%)
BTB 562..>643 CDD:279045
BTB 566..>643 CDD:197585
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 692..716
BTB 762..868 CDD:279045
BTB 770..872 CDD:197585
SPOP_C_like 872..>919 CDD:269810
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 976..1002
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1032..1094
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5184
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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