DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6678 and LOC100536575

DIOPT Version :9

Sequence 1:	NP_650996.1	Gene:	CG6678 / 42581	FlyBaseID:	FBgn0038917	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	XP_009295984.1	Gene:	LOC100536575 / 100536575	-ID:	-	Length:	409	Species:	Danio rerio

Alignment Length:	418	Identity:	118/418 - (28%)
Similarity:	167/418 - (39%)	Gaps:	125/418 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GFNAFGQ--HECVSGDVDCAAGFSELNAPV-STQNQCTISIG---------WRYAA----LAFGR 55
            |||.|||  ...|||.|.|     ::|:|| .:.::|...:.         |...|    ...|.
Zfish    40 GFNGFGQISRADVSGQVKC-----KVNSPVLISDDECKSGVNRSDRRIRACWSSRADLQQTQSGS 99

  Fly    56 KLCLRGLLDDGPNECVTLEATGNIRALAAADSHCLVLLQSGQLYRVQP-------KLQAELVAVR 113
            .:.|.|.: .||:..| ..:.|...||.:.....|......:|:.::|       |.:.||.|..
Zfish   100 GVYLSGCV-CGPSAQV-CASQGCTDALISETHLTLSFTDRVELWEIKPQQNQLVWKREHELSAEH 162

  Fly   114 LEAAPRSNSGTKRSIFGAAKAPSSPIIEHIACGSHINVAISSENCVYSIPSCLHQFSERQFRVKQ 178
            ..|.|..:.|               .::|                   .|...|..   :.....
Zfish   163 TAALPLVSGG---------------FVQH-------------------KPPFFHPL---KLCAVS 190

  Fly   179 LQCGHEHAVLLNANGDVFTWGNGLRGQLGLAELRVEETPQLLEALAGIKITQIAAGGWHSAAISA 243
            |..|.|||:||.|:|.:::||:|..||||...|...|.||.:|||.|:.|..:|||.|||||:|:
Zfish   191 LVLGSEHALLLTADGTLYSWGSGSHGQLGHGVLTSLEDPQAVEALWGVPIKAVAAGNWHSAAVSS 255

  Fly   244 FGDLYTWGLNCSGQLGLRVMKPGGVLKEPTVFPLPQLQDLPECACSQSGESNDDCAPL------- 301
            .||||.||.|.||||||           |:       :.|.|.....:|..||| .|:
Zfish   256 GGDLYMWGWNESGQLGL-----------PS-------RGLEEEKRRGNGSGNDD-QPINTDGKSR 301

  Fly   302 -----------------------RVFAGSRHTLLIRRCGRLWVSGWCKHGQLG----RQLQDLSY 339
                                   |:..|||||..:...|.|:..||.::||||    ....:.:.
Zfish   302 TDVFISIQAFPALVDIANMSEISRISCGSRHTAAVTSAGDLYTWGWGQYGQLGHGTEHSTDEPTP 366

  Fly   340 VDAFQALEGITMNPTVDDVLCGPWSTLL 367
            ||.|.     :.:.:|.||:||.|:|.:
Zfish   367 VDYFS-----SHSLSVKDVVCGSWNTFV 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6678	NP_650996.1	ATS1	<78..371	CDD:227511	94/331 (28%)
		RCC1_2	176..205	CDD:290274	12/28 (43%)
		RCC1	192..241	CDD:278826	24/48 (50%)
		RCC1_2	228..257	CDD:290274	18/28 (64%)
LOC100536575	XP_009295984.1	RCC1_2	189..217	CDD:290274	12/27 (44%)
		RCC1	204..253	CDD:278826	24/48 (50%)
		RCC1_2	240..269	CDD:290274	18/28 (64%)
		RCC1	257..336	CDD:278826	27/97 (28%)
		RCC1_2	323..352	CDD:290274	10/28 (36%)
		RCC1	340..389	CDD:278826	18/53 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595206
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	4	3.800