DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6678 and Rcc1

DIOPT Version :9

Sequence 1:	NP_650996.1	Gene:	CG6678 / 42581	FlyBaseID:	FBgn0038917	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_001184011.1	Gene:	Rcc1 / 100088	MGIID:	1913989	Length:	434	Species:	Mus musculus

Alignment Length:	352	Identity:	79/352 - (22%)
Similarity:	129/352 - (36%)	Gaps:	83/352 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 AFGQHECVSGDVDCAAGFSELNAPVSTQNQCTISIGWRY-AALAFGRKLCLRGLLDDGPNEC--- 70
            |.|:...|.|. :...|..||...|     ..:|.|..: |||....::.|.|...|.....
Mouse   111 ALGRDTSVEGS-EMVPGKVELQEKV-----VQVSAGDSHTAALTEDGRVFLWGSFRDNNGVIGLL 169

  Fly    71 ---------VTLEATGNIRALAAADSHCLVLLQSGQLYRVQPKLQAELVAVRLEAAPR--SNSGT 124
                     |.::....:..:|:.:.|.::|...|.||.:....|.:|..|     |.  :|.|.
Mouse   170 EPMKKSMVPVQVQLDAPVVKVASGNDHLVMLTNDGDLYTLGCGEQGQLGRV-----PELFANRGG 229

  Fly   125 KRSIFGAAKAPSSPII-----------EHIACGSHINVAISSENCVYS----------------- 161
            ::.: |....|...::           :...||::...|||.|..||.
Mouse   230 RQGL-GRLLVPRCVLLKSRGTRGRVRFQDAFCGAYFTFAISREGHVYGFGLSNYHQLGTPGTGSC 293

  Fly   162 -IPSCLHQFSERQFRVKQLQCGHEHAVLLNANGDVFTWGNGLRGQLGLAELRVEET-PQLLEALA 224
             ||..|..|............|..|.|.:::.|..::.|....|:|||.|...|:: |.|:..|.
Mouse   294 FIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLP 358

  Fly   225 GIKITQIAAGGWHSAAISAFGDLYTWGLNCSGQLGLRVMKPGGVLKEPTVFPLPQLQDLPECACS 289
              .::.:|.|.....|:|..|.::.||:..:.|||..                   ||  |.|.|
Mouse   359 --VVSSVACGASVGYAVSKDGRVFAWGMGTNYQLGTG-------------------QD--EDAWS 400

  Fly   290 ---QSGESNDDCAPLRVFAGSRHTLLI 313
               .:|:..::...|.|.:|.:||:|:
Mouse   401 PVEMTGKQLENRVVLTVSSGGQHTVLL 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6678	NP_650996.1	ATS1	<78..371	CDD:227511	62/271 (23%)
		RCC1_2	176..205	CDD:290274	5/28 (18%)
		RCC1	192..241	CDD:278826	13/49 (27%)
		RCC1_2	228..257	CDD:290274	7/28 (25%)
Rcc1	NP_001184011.1	RCC1	48..95	CDD:278826
		RCC1	98..147	CDD:278826	11/41 (27%)
		RCC1	150..200	CDD:278826	6/49 (12%)
		RCC1_2	187..216	CDD:290274	7/28 (25%)
		RCC1	203..268	CDD:278826	13/70 (19%)
		RCC1	271..322	CDD:278826	10/50 (20%)
		RCC1	325..368	CDD:278826	13/44 (30%)
		RCC1	376..427	CDD:278826	17/71 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910