DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6678 and herc4

DIOPT Version :9

Sequence 1:	NP_650996.1	Gene:	CG6678 / 42581	FlyBaseID:	FBgn0038917	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	XP_031760534.1	Gene:	herc4 / 100036667	XenbaseID:	XB-GENE-962981	Length:	1057	Species:	Xenopus tropicalis

Alignment Length:	363	Identity:	90/363 - (24%)
Similarity:	140/363 - (38%)	Gaps:	94/363 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 GPNECVTLE-------ATGNIRALAAADSHCLVLLQSGQLYRVQPKLQAELVAVRLEAAPRSNSG 123
            |.:|.|.||       ...|:|.:.....|.:.:|..|.:|........:|        ....|.
Frog    16 GIDEEVVLEPRRCDFFINKNVRDVGCGSRHTVFVLDDGTVYTCGCNDLGQL--------GHDKSR 72

  Fly   124 TKRSIFGAAKAPSSPIIEHIACGSHINVAISSENCVYS-------------------IPSCLHQF 169
            .|....||..|   .||..::||....:|::.:..|:|                   :|..:...
Frog    73 RKPEQVGALDA---QIIVAVSCGEAHTLALNDKGQVFSWGHAVYGQIGLSTAEEYIRVPRNIKSL 134

  Fly   170 SERQFRVKQLQCGHEHAVLLNANGDVFTWGNGLRGQLGLA-ELRVEETPQLLEALAGIKITQIAA 233
            |:.|  :.|:.|||.|::.|:.:.|:|:||....|||||. |::.|..|:.:::|:||....|||
Frog   135 SDVQ--IVQVACGHHHSLALSKDSDIFSWGQNQYGQLGLGLEIKKECAPRHIKSLSGIPFAHIAA 197

  Fly   234 GGWHSAAISAFGDLYTWGLNCSGQLGLRVMKPGGVLKEPTVFPLPQLQDLPECACSQS------- 291
            ||.||.|::..|.::.||.|..|||||.......|   |.:....:.|.:....|.:.
Frog   198 GGGHSFALTISGAIFGWGRNKFGQLGLTDETDRNV---PALLKSLRSQKIIHICCGEDHTAALTK 259

  Fly   292 -----------------GESNDDCAPLRVF-----------AGSRHTL-LIRRCGRLWVSGWCKH 327
                             ..:|.:..|.:||           .|.:||| .:...||::..|...:
Frog   260 EGGVFTFGAGGYGQLGHNSTNHEVNPRKVFELMGSIVTQIACGRQHTLAFVPSSGRIYSFGLGGN 324

  Fly   328 GQLGRQLQDLSYVDAFQALEGITMNPTVDDVLCGPWST 365
            ||||               .|.|:|......:.|.|.|
Frog   325 GQLG---------------TGSTINRKSPFTVKGNWLT 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6678	NP_650996.1	ATS1	<78..371	CDD:227511	85/344 (25%)
		RCC1_2	176..205	CDD:290274	10/28 (36%)
		RCC1	192..241	CDD:278826	22/49 (45%)
		RCC1_2	228..257	CDD:290274	12/28 (43%)
herc4	XP_031760534.1	ATS1	2..353	CDD:227511	90/363 (25%)
herc4	XP_031760534.1	HECTc	709..1055	CDD:238033
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010