DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dnd and Arl13b

DIOPT Version :9

Sequence 1:	NP_650995.1	Gene:	dnd / 42580	FlyBaseID:	FBgn0038916	Length:	179	Species:	Drosophila melanogaster
Sequence 2:	NP_080853.3	Gene:	Arl13b / 68146	MGIID:	1915396	Length:	427	Species:	Mus musculus

Alignment Length:	178	Identity:	61/178 - (34%)
Similarity:	102/178 - (57%)	Gaps:	10/178 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SLLRKLRPNPEKEARILLLGLDNAGKTTILKQLASEDITTVTPTAGFNIKSVAADGFKLNVWDIG 69
            :|.::.| .|.::..::::||||||||...|.:..|....|.||.||:...:....|::.::|:|
Mouse    10 NLFKRWR-EPVRKVTLVMVGLDNAGKTATAKGIQGEHPEDVAPTVGFSKIDLRQGKFQVTIFDLG 73

  Fly    70 GQWKIRPYWKNYFANTDVLIYVIDCTDRTRLPEAGSELFEMLMDNRLKQVPVLIFANKQDMPDAM 134
            |..:||..||||:|.:..:|:|:|.:|..|:.|....:.|:|...|:...|:|:.|||||...|:
Mouse    74 GGKRIRGIWKNYYAESYGVIFVVDSSDEERMEETKETMSEVLRHPRISGKPILVLANKQDKEGAL 138

  Fly   135 SAAEVAEKMSLVQLQGR---TWEIKACTAVDGTG------LKEGMDWV 173
            ..|:|.|.:||.:|...   ..:|:.|:||.|.|      :|:|:.|:
Mouse   139 GEADVIECLSLEKLVNEHKCLCQIEPCSAVLGYGKKIDKSIKKGLYWL 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dnd	NP_650995.1	Arl3	3..176	CDD:206721	61/178 (34%)
Arl13b	NP_080853.3	Arl2l1_Arl13_like	23..189	CDD:133361	58/164 (35%)
		Ras	24..172	CDD:278499	54/147 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	207..250
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	269..427
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0074
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810