DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dnd and arc-1

DIOPT Version :9

Sequence 1:	NP_650995.1	Gene:	dnd / 42580	FlyBaseID:	FBgn0038916	Length:	179	Species:	Drosophila melanogaster
Sequence 2:	NP_496089.3	Gene:	arc-1 / 174525	WormBaseID:	WBGene00000180	Length:	539	Species:	Caenorhabditis elegans

Alignment Length:	174	Identity:	60/174 - (34%)
Similarity:	95/174 - (54%)	Gaps:	15/174 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RKLRPNPEKEARILLLGLDNAGKTTILKQLASEDITTVT---PTAGFNIKSVAADGFKLNVWDIG 69
            |||......|:|::|||||.||||:|:::|....:.||.   ||.||||:::....::||.||:|
Worm   360 RKLHIGDFIESRVVLLGLDGAGKTSIVRRLKKVQMDTVMAPHPTIGFNIETIHYKNYRLNFWDVG 424

  Fly    70 GQWKIRPYWKNYFANTDVLIYVIDCTDRTRLPEAGSELFEMLMDNRLKQVPVLIFANKQD---MP 131
            |..|:|..||:|::|...:.||||.....|..||..||..::.|..:...||::..|::|   :.
Worm   425 GLPKLRHLWKHYYSNAQAIFYVIDGYAVERFSEAIKELNRVMSDPLVGTCPVIVAVNRKDGYALN 489

  Fly   132 DAMSAAEVAEKMSLVQLQGRTWE--IKACTAVDGTGLKEGMDWV 173
            ..|.|.       |.||:...::  ...|.|..|:|:.:.:|.:
Worm   490 GHMDAL-------LSQLEALPFQHHFHCCDAATGSGIDQIIDQI 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dnd	NP_650995.1	Arl3	3..176	CDD:206721	60/174 (34%)
arc-1	NP_496089.3	zf-RING_5	6..54	CDD:291308
		zf-B_box	105..149	CDD:279037
		Apolipoprotein	201..>306	CDD:279749
		BBC	208..339	CDD:128778
		Arf_Arl	371..526	CDD:206644	56/161 (35%)
		small_GTP	371..526	CDD:272973	56/161 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910