DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17819 and Trim23

DIOPT Version :9

Sequence 1:	NP_650994.1	Gene:	CG17819 / 42579	FlyBaseID:	FBgn0038915	Length:	186	Species:	Drosophila melanogaster
Sequence 2:	XP_008758905.1	Gene:	Trim23 / 81002	RGDID:	621587	Length:	601	Species:	Rattus norvegicus

Alignment Length:	189	Identity:	63/189 - (33%)
Similarity:	104/189 - (55%)	Gaps:	24/189 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 PVSFIK--KILPAGSQKSCLLILGLDNAGKSTLTDRLAEI----------FNGESKESNNQVSEW 58
            ||:|.|  ::......:..::.||||.|||:|:..:|.:.          ||.|:.|..|    .
  Rat   415 PVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYKN----L 475

  Fly    59 SFTINNFRVQLWDINGELKNRQIWPKYYKKVNVLIFVLDSTDALRLSEARCVLCDVLMHQELDNA 123
            .|||       ||:.|:.|.|.:|..||.....::||:||:...|:|||...|..:|..:||.:|
  Rat   476 KFTI-------WDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRISEAHSELAKLLTEKELRDA 533

  Fly   124 PLLIVSNKKDASGSLSMSTVIDLMGLYRL-TGRDWTFEECSMRTGSGVQEIVNWINEKI 181
            .|||.:||:|.:|:||:..:.:|:.|::| .||.|..:.|..|:|.|:.|.::|::.::
  Rat   534 LLLIFANKQDVAGALSVEEITELLSLHKLCCGRSWYIQGCDARSGMGLYEGLDWLSRQL 592

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17819	NP_650994.1	Arf_Arl	22..180	CDD:206644	59/168 (35%)
CG17819	NP_650994.1	Ras	23..183	CDD:278499	59/170 (35%)
Trim23	XP_008758905.1	zf-RING_UBOX	58..100	CDD:290181
		BBOX	152..195	CDD:237988
		BBOX	200..246	CDD:197662
		BBC	253..397	CDD:128778
		ARD1	433..601	CDD:206723	59/171 (35%)
		Ras	433..592	CDD:278499	59/169 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0070
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810