DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17819 and trim23

DIOPT Version :9

Sequence 1:	NP_650994.1	Gene:	CG17819 / 42579	FlyBaseID:	FBgn0038915	Length:	186	Species:	Drosophila melanogaster
Sequence 2:	XP_005155659.1	Gene:	trim23 / 767706	ZFINID:	ZDB-GENE-060929-804	Length:	576	Species:	Danio rerio

Alignment Length:	189	Identity:	61/189 - (32%)
Similarity:	101/189 - (53%)	Gaps:	24/189 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 PVSFIK--KILPAGSQKSCLLILGLDNAGKSTLTDRLAEI----------FNGESKESNNQVSEW 58
            ||:|.|  ::......:..::.||||.|||:|:..:|.:.          ||.|:.|..|    .
Zfish   390 PVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYKN----L 450

  Fly    59 SFTINNFRVQLWDINGELKNRQIWPKYYKKVNVLIFVLDSTDALRLSEARCVLCDVLMHQELDNA 123
            .|||       ||:.|:.|.|.:|..||.....::||:||....||.|:...|..:|..:||.:|
Zfish   451 KFTI-------WDVGGKHKLRPLWKHYYLNTQAVVFVIDSCHRDRLMESHSELAKLLTEKELRDA 508

  Fly   124 PLLIVSNKKDASGSLSMSTVIDLMGLYRL-TGRDWTFEECSMRTGSGVQEIVNWINEKI 181
            .|||.:||:|..|::|:..:.:|:.|::| .||.|..:.|..|:|.|:.|.::|::.::
Zfish   509 LLLIFANKQDVPGAVSVEEMTELLSLHKLCCGRSWHIQGCDARSGMGLHEGLDWLSRQL 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17819	NP_650994.1	Arf_Arl	22..180	CDD:206644	57/168 (34%)
CG17819	NP_650994.1	Ras	23..183	CDD:278499	57/170 (34%)
trim23	XP_005155659.1	RING	33..76	CDD:214546
		BBOX	127..170	CDD:237988
		BBOX	175..221	CDD:197662
		iSH2_PI3K_IA_R	228..372	CDD:304922
		ARD1	408..576	CDD:206723	57/171 (33%)
		Ras	408..567	CDD:278499	57/169 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0070
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810