DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6656 and ACP2

DIOPT Version :9

Sequence 1:	NP_650991.1	Gene:	CG6656 / 42576	FlyBaseID:	FBgn0038912	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_001343945.1	Gene:	ACP2 / 53	HGNCID:	123	Length:	434	Species:	Homo sapiens

Alignment Length:	360	Identity:	114/360 - (31%)
Similarity:	184/360 - (51%)	Gaps:	19/360 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 RNLRMISILFRHGAKNPSGFYPLDPHAAHDWQGGMGALTPKGSLQAYNLGRNLRMRYYRLLPPNS 104
            |:||.:::|:|||.::|...||.||:...:|..|.|.||.:|.||.:.||:.||.||:..|  |:
Human    31 RSLRFVTLLYRHGDRSPVKTYPKDPYQEEEWPQGFGQLTKEGMLQHWELGQALRQRYHGFL--NT 93

  Fly   105 LYTQQQVNVLSSAAERCVMSAQSVLAGMMPPLENKNVLP-IPWQPVAVNTLSRNEDILLA-QKKP 167
            .|.:|:|.|.|:..:|.:|||::.|||:.||...:...| |.|||:.|:|:...||.||. ...|
Human    94 SYHRQEVYVRSTDFDRTLMSAEANLAGLFPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLGP 158

  Fly   168 CLKYDHILQKLYKSPPPELQKLNEDNMELYKLLTKNTGKNISNVLDVELLYGTLKTEEEANLVLP 232
            |.:|:.:..:..::  ||.|..:..|.:...::...||.....:..|..:|.||..|:...|.||
Human   159 CPRYEQLQNETRQT--PEYQNESSRNAQFLDMVANETGLTDLTLETVWNVYDTLFCEQTHGLRLP 221

  Fly   233 DWTENIYPEEIRPLAERSY-MLF--TETNLMKRIKGGAFLTDILNKMQNKRKRNLNPDRKIFLYS 294
            .|......:.:..|.:.|: .||  .:.....|::||..|..|...:......:..|  |:.:||
Human   222 PWASPQTMQRLSRLKDFSFRFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLP--KLLVYS 284

  Fly   295 GHDVTLVNVMNSLGILDQTTKLPEYASALAFELHHSKSFSDGDFEVKLVYYYNSEDKFPKELTIP 359
            .||.|||.:..:|.:.:  .:...|||...|||:...|   |:|.|:: |:.|..||.|..|::|
Human   285 AHDTTLVALQMALDVYN--GEQAPYASCHIFELYQEDS---GNFSVEM-YFRNESDKAPWPLSLP 343

  Fly   360 NCDAPCSLTQFEASVKALLLDNYDETCE--NHPTD 392
            .|...|.|..|....:.::..::.:.|:  :.|.|
Human   344 GCPHRCPLQDFLRLTEPVVPKDWQQECQLASGPAD 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6656	NP_650991.1	HP_HAP_like	41..344	CDD:132717	99/307 (32%)
ACP2	NP_001343945.1	HP_HAP_like	33..330	CDD:132717	100/308 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1221585at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11567
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R958
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	6.050