Protein Alignment Cby and Cby1

DIOPT Version :10

• Sequence 1: NP_650989.7
• Gene: Cby / 42574
• FlyBaseID: FBgn0067317
• Length: 133
• Species: Drosophila melanogaster
• Sequence 2: NP_082910.1
• Gene: Cby1 / 73739
• MGIID: 1920989
• Length: 127
• Species: Mus musculus
• Alignment Length: 117
• Identity: 43/117 - (36%)
• Similarity: 66/117 - (56%)
• Gaps: 12/117 - (10%)

  Fly    26 MPLFNKKFESKPIPVRQGR--CNIGHPV--ATEDLD---DFRQISLTLGNKELRFADGIWM-HST 82
            ||||...|..|..|.|:..  .|: |.:  :|.:|:   |:...::.|..:.|:|.:|.|: .|.
Mouse     1 MPLFGSIFSPKKTPPRKSASLSNL-HSLDRSTRELELGLDYGTPTMNLAGQSLKFENGQWVADSV 64

  Fly    83 RKGDVD--DMLRLNKKFRALEEENNMCNLKIEVMLDLLAEHATELSELKPKE 132
            ..|.||  :..||.|:.:.||||||:..||::::||:|:|...| |.||.||
Mouse    65 ISGGVDRRETQRLRKRNQQLEEENNLLRLKVDILLDMLSETTAE-SHLKDKE 115

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cby	NP_650989.7	Cby_like	26..124	CDD:143631	37/107 (35%)
Cby1	NP_082910.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25		9/24 (38%)
		Chibby	2..115	CDD:464233	40/114 (35%)
		Minimal region for the interaction with PKD2. /evidence=ECO:0000250|UniProtKB:Q9Y3M2	60..112		21/52 (40%)
		Leucine-zipper, mediates homodimerization. /evidence=ECO:0000250|UniProtKB:Q9Y3M2	77..98		10/20 (50%)