DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cby and Cby2

DIOPT Version :9

Sequence 1:	NP_650989.6	Gene:	Cby / 42574	FlyBaseID:	FBgn0067317	Length:	132	Species:	Drosophila melanogaster
Sequence 2:	NP_001157611.1	Gene:	Cby2 / 67926	MGIID:	1915176	Length:	446	Species:	Mus musculus

Alignment Length:	140	Identity:	29/140 - (20%)
Similarity:	49/140 - (35%)	Gaps:	44/140 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 PLFNKKFESKPI-PVRQGRCNIGHPVATEDLD-DFRQISLTLGNKELRFADGIW----------- 78
            ||  .:|.|.|. |:.:       |.:..||: |:....:.|.::...|.||.|
Mouse    90 PL--NRFSSMPFDPMER-------PTSQADLELDYNPPRVQLSDEMFVFQDGRWVNESCRLQPPY 145

  Fly    79 ----------MHSTRKGDVDDMLRLNKKF----RALEEENNMCNLKIEVM--------LDLLAEA 121
                      :|..|......:...||..    |||.:||.....:.:::        :.|..|.
Mouse   146 FSPPSSFHHKLHHRRLAKEYQLQEENKSLRDENRALRDENKALRKENKILQVFWEEHKVTLGHEE 210

  Fly   122 TELSELKPKE 131
            ::.|.|..|:
Mouse   211 SQTSSLLHKD 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cby	NP_650989.6	None
Cby2	NP_001157611.1	Cby_like	76..191	CDD:143631	24/109 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	208..243		4/13 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	268..317
		Cby_like	302..424	CDD:299860
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010