DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Cby and CBY3

DIOPT Version :9

Sequence 1:NP_650989.6 Gene:Cby / 42574 FlyBaseID:FBgn0067317 Length:132 Species:Drosophila melanogaster
Sequence 2:NP_001157916.1 Gene:CBY3 / 646019 HGNCID:33278 Length:242 Species:Homo sapiens


Alignment Length:162 Identity:38/162 - (23%)
Similarity:56/162 - (34%) Gaps:47/162 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 LATFCCPSSISDSQPLPFKQLFAMPLFNKKFESKPIPVRQGRCNIGHPVATEDLDDF-------R 60
            ||||.|.::...|:.....|.|.....::.|..:..|:|:          ...|..|       |
Human    58 LATFECSATSHASRLWQTLQQFWADHISRPFSPRRPPLRR----------MPSLSTFYLLDHNTR 112

  Fly    61 QISL---------TLGNKELRFADGIW-----MHSTR-----------KGDVDDMLRLNKKFRAL 100
            |..|         .|.|:...|..|.|     :..||           |..|.     ..|.:.|
Human   113 QAELGLAYGAPCMRLSNQAFVFRGGRWTTESQLARTRSPLLSRTAWGWKAQVQ-----RSKSQVL 172

  Fly   101 EEENNMCNLKIEVMLDLLAEATELSELKPKEK 132
            .||||...|:.|:::|:|.|......|..|::
Human   173 LEENNYLKLQQELLIDMLTETMARMHLLEKQR 204

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CbyNP_650989.6 None
CBY3NP_001157916.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..49
Chibby 94..202 CDD:291318 28/122 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 53 1.000 Domainoid score I11361
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR21533
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
33.010

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