DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lsn and SNF8

DIOPT Version :9

Sequence 1:	NP_650987.1	Gene:	lsn / 42572	FlyBaseID:	FBgn0260940	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_009172.2	Gene:	SNF8 / 11267	HGNCID:	17028	Length:	258	Species:	Homo sapiens

Alignment Length:	253	Identity:	129/253 - (50%)
Similarity:	182/253 - (71%)	Gaps:	6/253 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 RRRVGLGAIQQQKLAAEKYKDKGTDLQENQLEQMTKQMEVFRVKLEEFAMKHKEDIRKNSQFRKQ 66
            ||.||.|||.::|||..|||::||.|.|:||.||:||:::|:..|||||.|||::||||.:||.|
Human     3 RRGVGAGAIAKKKLAEAKYKERGTVLAEDQLAQMSKQLDMFKTNLEEFASKHKQEIRKNPEFRVQ 67

  Fly    67 FQEMCAAIGVDPLATGKGFWS-VLGMGDFYYELGVQVVEVCLAANHKTGGLMELDDLRRRLIAAR 130
            ||:|||.|||||||:|||||| :||:||||||||||::|||||..|:.|||:.|::|.::::..|
Human    68 FQDMCATIGVDPLASGKGFWSEMLGVGDFYYELGVQIIEVCLALKHRNGGLITLEELHQQVLKGR 132

  Fly   131 GQSSVHQEITKEDILMAAKKLSIFGNGFVVHKLGKGKYIVQSIPGELSMEETNILNAASNTEQGC 195
            |:.:  |:::::|::.|.|||...|.||.:..:| |.|::||:|.||:|:.|.:|..|.  :.|.
Human   133 GKFA--QDVSQDDLIRAIKKLKALGTGFGIIPVG-GTYLIQSVPAELNMDHTVVLQLAE--KNGY 192

  Fly   196 VTQSQLIKDLGWTDYRAQQSLDKVLGEGLCWIDKQAGDEPAYWFPSLFPGRNAQTTAA 253
            ||.|::...|.|...||:|.|:.:|.|||.|:|.||..|..||.|:||....:|...|
Human   193 VTVSEIKASLKWETERARQVLEHLLKEGLAWLDLQAPGEAHYWLPALFTDLYSQEITA 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lsn	NP_650987.1	EAP30	6..228	CDD:282067	115/222 (52%)
SNF8	NP_009172.2	EAP30	6..225	CDD:398021	116/223 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157815
Domainoid	1	1.000	238	1.000	Domainoid score	I2315
eggNOG	1	0.900	-	-		E1_KOG3341
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5239
Inparanoid	1	1.050	258	1.000	Inparanoid score	I3141
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54473
OrthoDB	1	1.010	-	-		D554010at33208
OrthoFinder	1	1.000	-	-		FOG0004178
OrthoInspector	1	1.000	-	-		oto90352
orthoMCL	1	0.900	-	-		OOG6_102942
Panther	1	1.100	-	-	LDO	PTHR12806
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3694
SonicParanoid	1	1.000	-	-		X3997
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800