DRSC/TRiP Functional Genomics Resources

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Protein Alignment CASK and CPK29

DIOPT Version :9

Sequence 1:NP_001262811.1 Gene:CASK / 42567 FlyBaseID:FBgn0013759 Length:929 Species:Drosophila melanogaster
Sequence 2:NP_974150.2 Gene:CPK29 / 843936 AraportID:AT1G76040 Length:561 Species:Arabidopsis thaliana


Alignment Length:505 Identity:128/505 - (25%)
Similarity:215/505 - (42%) Gaps:130/505 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 VYELCEVIGKGPFSIVRRCIHRESNQQFAVKIVDVAKFTASPGLSTADLKREATIC-HMLKHPHI 74
            :|:|.:.:|:|.|.|..:|..:.:.:::|.|.:...|......:.  |::||..|. |:...|:|
plant   111 LYDLHKELGRGQFGITYKCTDKSNGREYACKSISKRKLIRRKDIE--DVRREVMILQHLTGQPNI 173

  Fly    75 VELLETYSSEGMLYMVFEFMEGSDLCFEVVRRAVAGFVYSEAVACHYMRQILEALRYCHENDILH 139
            ||....|..:..|::|.|...|.:|...::::.    .|||..|.:..|||:..:..||...::|
plant   174 VEFRGAYEDKDNLHLVMELCSGGELFDRIIKKG----SYSEKEAANIFRQIVNVVHVCHFMGVVH 234

  Fly   140 RDVRPACALLATVDNSAPVKLGGFGSAIQLPGTRETIETHGR-----VGCPHYMAPEVVTRRLYG 199
            ||::|...||.:.:..:|:|...||.::.:        ..|:     ||..:|:||||:.|. ||
plant   235 RDLKPENFLLVSNEEDSPIKATDFGLSVFI--------EEGKVYRDIVGSAYYVAPEVLHRN-YG 290

  Fly   200 KGCDVWGAGVMLHVLLSGRLPFLGSGVR-LQQSVARGRLSFEAPEWKSISANAKDLVMKMLAANP 263
            |..|||.|||||::||||..||.|...: :.:::..|:|..|...|.:||.:||||:.|||..:|
plant   291 KEIDVWSAGVMLYILLSGVPPFWGETEKTIFEAILEGKLDLETSPWPTISESAKDLIRKMLIRDP 355

  Fly   264 HHRLSITEVLDHPWIRDRDKLQRTHLAD------TVEELKRYNARRKLKG-AVQAIAGGTNMDPL 321
            ..|::..|.|:|||:.|      |.::|      .:..:|::.|..|||. |::.||        
plant   356 KKRITAAEALEHPWMTD------TKISDKPINSAVLVRMKQFRAMNKLKKLALKVIA-------- 406

  Fly   322 YATDADMPITGATDEWADEEAGIEAVQRILDCLDDIYSLQDAHVDADVLRDMLRDNRLHQFLQLF 386
                         :..::||         :..|...:...|......:..|.|| |.||:     
plant   407 -------------ENLSEEE---------IKGLKQTFKNMDTDESGTITFDELR-NGLHR----- 443

  Fly   387 DRIAATVVTSNGRAPAAEAVGRCRDVLEQLSSTSGGNSLGGKYAKEELMRLLAAPHMQ------- 444
                                                  ||.|..:.|:.:|:.|..:.       
plant   444 --------------------------------------LGSKLTESEIKQLMEAADVDKSGTIDY 470

  Fly   445 -----ALLHSHDVVARDVYGEEALRVTPPPMVPYLNGDELDNVEGGELQH 489
                 |.:|.|. :.::....||.:        |.:.|....:...||:|
plant   471 IEFVTATMHRHR-LEKEENLIEAFK--------YFDKDRSGFITRDELKH 511

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CASKNP_001262811.1 STKc_CASK 8..308 CDD:270996 99/310 (32%)
S_TKc 12..278 CDD:214567 90/272 (33%)
L27 347..396 CDD:280918 8/48 (17%)
L27 406..462 CDD:280918 9/67 (13%)
PDZ_signaling 493..573 CDD:238492
SH3_CASK 586..646 CDD:213014
Guanylate_kin 710..883 CDD:279019
GuKc 720..883 CDD:214504
CPK29NP_974150.2 S_TKc 112..370 CDD:214567 90/272 (33%)
STKc_CAMK 112..369 CDD:270687 89/271 (33%)
PTZ00184 405..548 CDD:185504 28/190 (15%)
EFh 417..476 CDD:238008 14/102 (14%)
EFh 489..549 CDD:238008 7/31 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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