Protein Alignment CASK and camk2g1

DIOPT Version :9

• Sequence 1: NP_001262811.1
• Gene: CASK / 42567
• FlyBaseID: FBgn0013759
• Length: 929
• Species: Drosophila melanogaster
• Sequence 2: XP_005156418.1
• Gene: camk2g1 / 791855
• ZFINID: ZDB-GENE-050913-146
• Length: 627
• Species: Danio rerio
• Alignment Length: 588
• Identity: 176/588 - (29%)
• Similarity: 268/588 - (45%)
• Gaps: 110/588 - (18%)

  Fly     8 FDDVYELCEVIGKGPFSIVRRCIHRESNQQFAVKIVDVAKFTASPGLSTAD---LKREATICHML 69
            |.|.|:|.|.:|||.||:||||:.:.:.|::|.||::..|      ||..|   |:|||.||.:|
Zfish    10 FTDEYQLYEELGKGAFSVVRRCVKKSTGQEYAAKIINTKK------LSARDHQKLEREARICRLL 68

  Fly    70 KHPHIVELLETYSSEGMLYMVFEFMEGSDLCFEVVRRAVAGFVYSEAVACHYMRQILEALRYCHE 134
            |||:||.|.::.|.||..|:||:.:.|.:|..::|.|.    .||||.|.|.:.||||::.:.|:
Zfish    69 KHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCISQILESVNHIHQ 129

  Fly   135 NDILHRDVRPACALLATVDNSAPVKLGGFGSAIQLPGTRETIETHGRVGCPHYMAPEVVTRRLYG 199
            :||:|||::|...|||:....|.|||..||.||::.|.::.  ..|..|.|.|::|||:.:..||
Zfish   130 HDIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQA--WFGFAGTPGYLSPEVLRKDPYG 192

  Fly   200 KGCDVWGAGVMLHVLLSGRLPFLGSGV-RLQQSVARGRLSFEAPEWKSISANAKDLVMKMLAANP 263
            |..|:|..||:|::||.|..||..... :|.|.:..|...|.:|||.:::..||:|:.:||..||
Zfish   193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINP 257

  Fly   264 HHRLSITEVLDHPWIRDRDKL-QRTHLADTVEELKRYNARRKLKGAVQAI--------AGGTNMD 319
            ..|::..:.|.|||:..|..: ...|..:|||.|:::|||||||||:...        .|..:..
Zfish   258 AKRITAEQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQHTS 322

  Fly   320 PLYATDADMPITGATDEWADEEAGIEAVQRILDCLDDIYSLQDAHVDADVLRDMLRDNRLHQFLQ 384
            |...|.:    |.|..:        ||.:.:|            :..||.::        ||
Zfish   323 PAAPTTS----TAALAQ--------EACKSLL------------NKKADGVK--------HQ--- 352

  Fly   385 LFDRIAATVVTSNGRAPAAEAVGRCRDVLEQLSST---------------SGGNSLGGKYAKEEL 434
                      |:|.:.....||..........|||               ..|::......:||.
Zfish   353 ----------TNNTKNSVVSAVVNAMKESNTASSTPMEPQTTVVHNPVDGPKGSTESCNTNEEED 407

  Fly   435 MRLLAAPHMQALLHSHDVVARDVYGEE--ALRVTP---PPMVPYLNGDELDNVEGGELQHVTRVR 494
            |:...|...|.......|:::...|||  ||..:|   |..||.   .::..:......|.:.
Zfish   408 MKGRKAESAQGASSDSAVMSQCSAGEEPPALVASPQGSPSTVPV---HDIKRLAWNSSGHCSE-- 467

  Fly   495 LVQFQKNTDEPMGITLKMTEDGRCIVARIMHGGMIHRQATLHVGDEIREINGQPVQHQSVGQLQR 559
                           |:..:.|.|..|..:...|....|......||.:|..|.::..:.|..:.
Zfish   468 ---------------LERAQSGPCATAHGLGSVMASASAAQSRKQEIIKITEQLIEAVNNGDFEA 517

  Fly   560 MLR 562
            ..|
Zfish   518 YTR 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CASK	NP_001262811.1	STKc_CASK	8..308	CDD:270996	126/304 (41%)
		S_TKc	12..278	CDD:214567	110/269 (41%)
		L27	347..396	CDD:280918	5/48 (10%)
		L27	406..462	CDD:280918	14/72 (19%)
		PDZ_signaling	493..573	CDD:238492	12/70 (17%)
		SH3_CASK	586..646	CDD:213014
		Guanylate_kin	710..883	CDD:279019
		GuKc	720..883	CDD:214504
camk2g1	XP_005156418.1	STKc_CaMKII	12..303	CDD:270988	125/302 (41%)
		S_TKc	14..272	CDD:214567	110/269 (41%)
		CaMKII_AD	495..622	CDD:285524	6/26 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0033
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810