DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CASK and CG11811

DIOPT Version :9

Sequence 1:	NP_001262811.1	Gene:	CASK / 42567	FlyBaseID:	FBgn0013759	Length:	929	Species:	Drosophila melanogaster
Sequence 2:	NP_648408.1	Gene:	CG11811 / 39213	FlyBaseID:	FBgn0036099	Length:	233	Species:	Drosophila melanogaster

Alignment Length:	141	Identity:	43/141 - (30%)
Similarity:	76/141 - (53%)	Gaps:	3/141 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   712 KTLVLLGAHGVGRRHIKNTLISKYPDKYAYPIPHTTRPAKPEEENGRSYYFVSHDEMMADIGANE 776
            :.|||.|..|.|:..:...|.:::|..:.:.|.||||..:..||:|..||||...||.|.|..:|
  Fly    36 RPLVLCGPSGSGKSTLLKRLFAEFPSTFGFSISHTTRKPREGEEHGVHYYFVERPEMEAAIAGDE 100

  Fly   777 YLEYGTHEDAMYGTKLDTIRRIHTEGKMAILDVEPQALKILRTAEFTPYVVFIAAPSLQNIADYD 841
            ::|.......:|||....:|.|..:|::.|||:|.:.::.::..:..|.::|...||::.:   :
  Fly   101 FIETAEFTGNLYGTSKAAVREIQAQGRVCILDIEQKGVEQIKRTDLNPILIFNNPPSIKEL---E 162

  Fly   842 GSLERLAKESE 852
            ..|.:...|:|
  Fly   163 RRLRKRGSETE 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CASK	NP_001262811.1	STKc_CASK	8..308	CDD:270996
		S_TKc	12..278	CDD:214567
		L27	347..396	CDD:280918
		L27	406..462	CDD:280918
		PDZ_signaling	493..573	CDD:238492
		SH3_CASK	586..646	CDD:213014
		Guanylate_kin	710..883	CDD:279019	43/141 (30%)
		GuKc	720..883	CDD:214504	39/133 (29%)
CG11811	NP_648408.1	Guanylate_kin	34..219	CDD:279019	43/141 (30%)
CG11811	NP_648408.1	guanyl_kin	36..216	CDD:213788	43/141 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0194
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810