Protein Alignment CG6800 and Cilk1

DIOPT Version :10

• Sequence 1: NP_650984.1
• Gene: CG6800 / 42562
• FlyBaseID: FBgn0038902
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_064371.2
• Gene: Cilk1 / 56542
• MGIID: 1934157
• Length: 629
• Species: Mus musculus
• Alignment Length: 284
• Identity: 97/284 - (34%)
• Similarity: 160/284 - (56%)
• Gaps: 11/284 - (3%)

  Fly     7 SRYKMLEKIGEGVHGCVFKAIDLQRNKEVAIKKVALKNKF--GNIALNTLREIKTLQLCKSEYIL 69
            :||..::::|:|.:|.|.....::..:.:||||  :|.||  ....:| |||:|:|:......|:
Mouse     2 NRYTTIKQLGDGTYGSVLLGRSIESGELIAIKK--MKRKFYSWEECMN-LREVKSLKKLNHANIV 63

  Fly    70 DIIDIYPDLTGLSLVLEYQPDTLYNRLKSEVNPLSRQQVRKFAHQMFKGIAYLHEAGLMHRDIKP 134
            .:.::..:...|..:.||..:.||..:|..........:|...:|:.:|:|::|:.|..|||:||
Mouse    64 KLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKP 128

  Fly   135 ANLLISDTDMLKIADFGLARLYFPEDESR-LYSPQVSTRWYRAPEILFGSQKYGTGVDMWAAGCV 198
            .|||....:::|||||||||    |..|| .|:..||||||||||:|..|..|.:.:|:||.||:
Mouse   129 ENLLCMGPELVKIADFGLAR----EIRSRPPYTDYVSTRWYRAPEVLLRSTNYSSPIDIWAVGCI 189

  Fly   199 VAEMLRGVPLFAGTTDIEQLAIIIRTLGSPRLNQWPELTSLPDYSKIRFPNSVGIHWDNLFPSCT 263
            :||:....|||.|.::|:.:..|.:.||:|:...|||...|.......:|..:..:...|.|:.:
Mouse   190 MAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFLWPQCIPNNLKTLIPNAS 254

  Fly   264 HAVEINLVSNLVVYNPKNRLKASE 287
             :..|.|:.:|:.::||.|..||:
Mouse   255 -SEAIQLLRDLLQWDPKKRPTASQ 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6800	NP_650984.1	STKc_CCRK	8..295	CDD:270826	97/283 (34%)
Cilk1	NP_064371.2	STKc_MAK_like	4..284	CDD:270824	96/282 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	292..376
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	455..483
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	581..629