DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6800 and Cdk20

DIOPT Version :9

Sequence 1:	NP_650984.1	Gene:	CG6800 / 42562	FlyBaseID:	FBgn0038902	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_001020923.2	Gene:	Cdk20 / 364666	RGDID:	1305219	Length:	346	Species:	Rattus norvegicus

Alignment Length:	281	Identity:	123/281 - (43%)
Similarity:	181/281 - (64%)	Gaps:	3/281 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RYKMLEKIGEGVHGCVFKAIDLQRNKEVAIKKVALKNKFGNIALNTLREIKTLQ-LCKSEYILDI 71
            :|.:|.:||||.||.||||..::..:.||:|||||:.....|....|||||.|| :..|:|::.:
  Rat     3 QYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIEDSQYVVQL 67

  Fly    72 IDIYPDLTGLSLVLEYQPDTLYNRLKSEVNPLSRQQVRKFAHQMFKGIAYLHEAGLMHRDIKPAN 136
            ..::|...|..|..|:....|...::....||:..||:.:...:.||:|:.|...::|||:||||
  Rat    68 KAVFPHGAGFVLAFEFMLSDLAEVVRHAQRPLAPAQVKSYLQMLLKGVAFCHANNIVHRDLKPAN 132

  Fly   137 LLISDTDMLKIADFGLARLYFPEDESRLYSPQVSTRWYRAPEILFGSQKYGTGVDMWAAGCVVAE 201
            ||||.:..||||||||||::.| |..|||:.||:||||||||:|:|:::|..|||:||.||::.|
  Rat   133 LLISASGQLKIADFGLARVFSP-DGGRLYTHQVATRWYRAPELLYGARQYDQGVDLWAVGCIMGE 196

  Fly   202 MLRGVPLFAGTTDIEQLAIIIRTLGSPRLNQWPELTSLPDYSKIRFPNSVGIHWDNLFPSCTHAV 266
            :|.|.|||.|..|||||..::|.||:|....|||:|.||||:||.|.....:..:.:.|..:|..
  Rat   197 LLNGSPLFPGENDIEQLCCVLRILGTPSPRVWPEITELPDYNKISFKEQAPVPLEEVLPDASHQA 261

  Fly   267 EINLVSNLVVYNPKNRLKASE 287
             ::|:...::|.|:.|:.||:
  Rat   262 -LDLLGQFLLYPPRQRIAASQ 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6800	NP_650984.1	STKc_CCRK	8..295	CDD:270826	123/281 (44%)
CG6800	NP_650984.1	S_TKc	9..288	CDD:214567	123/280 (44%)
Cdk20	NP_001020923.2	STKc_CCRK	3..289	CDD:270826	123/281 (44%)
Cdk20	NP_001020923.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	298..324
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350405
Domainoid	1	1.000	247	1.000	Domainoid score	I2098
eggNOG	1	0.900	-	-		E1_KOG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H8109
Inparanoid	1	1.050	249	1.000	Inparanoid score	I3163
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1367115at2759
OrthoFinder	1	1.000	-	-		FOG0008130
OrthoInspector	1	1.000	-	-		oto98478
orthoMCL	1	0.900	-	-		OOG6_106079
Panther	1	1.100	-	-	LDO	PTHR24056
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6084
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.760