DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Burs and VWF

DIOPT Version :9

Sequence 1:NP_650983.1 Gene:Burs / 42560 FlyBaseID:FBgn0038901 Length:173 Species:Drosophila melanogaster
Sequence 2:NP_000543.3 Gene:VWF / 7450 HGNCID:12726 Length:2813 Species:Homo sapiens


Alignment Length:98 Identity:24/98 - (24%)
Similarity:39/98 - (39%) Gaps:13/98 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 DDCQ------VTPVIHVLQYPGCVPK-PIPSFACVGRCASYIQVSGSKIWQMERSCMCCQESGER 107
            |.|:      :|..:..::...|..: .:....|.|:|||....| ..|..::..|.||..:...
Human  2717 DTCEEPECNDITARLQYVKVGSCKSEVEVDIHYCQGKCASKAMYS-IDINDVQDQCSCCSPTRTE 2780

  Fly   108 EAAVSLFCPKVKPGERKFKKVLTKAPLECMCRP 140
            ...|:|.|..   |...:.:||.  .:||.|.|
Human  2781 PMQVALHCTN---GSVVYHEVLN--AMECKCSP 2808

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BursNP_650983.1 GHB_like 50..138 CDD:419725 22/94 (23%)
VWFNP_000543.3 VWD 35..179 CDD:395046
C8 222..291 CDD:214843
TIL 295..348 CDD:410995
VWC 350..>394 CDD:327433
VWD 377..540 CDD:214566
C8 584..648 CDD:400886
TIL 652..707 CDD:410995
Amino-terminal 764..787
E1 788..833
TIL <788..827 CDD:410995
CX 826..853
VWD 856..1011 CDD:214566
C8 1053..1127 CDD:214843
TIL 1146..1196 CDD:410995
VWA_N2 1198..1276 CDD:406551
VWA 1277..1449 CDD:214621
VWA 1498..1658 CDD:395045
VWA 1691..1862 CDD:395045
VWD 1950..2102 CDD:395046
C8 2138..2199 CDD:400886
TIL 2203..2254 CDD:410995
E2 2216..2261
VWC 2261..2321 CDD:214564
VWC 2431..2494 CDD:214564
Cell attachment site 2507..2509
VWC 2582..2644 CDD:278520
CT 2727..2808 CDD:214482 21/86 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1216
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.