DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Burs and TECTA

DIOPT Version :9

Sequence 1:	NP_650983.1	Gene:	Burs / 42560	FlyBaseID:	FBgn0038901	Length:	173	Species:	Drosophila melanogaster
Sequence 2:	NP_005413.2	Gene:	TECTA / 7007	HGNCID:	11720	Length:	2155	Species:	Homo sapiens

Alignment Length:	145	Identity:	32/145 - (22%)
Similarity:	55/145 - (37%)	Gaps:	22/145 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 ILKLCTAQPDSSVAATDNDITHLGDDC--QVTPVIHVLQ--YPGCVPKPIPSFAC--VGRCASYI 84
            :.:||:..|:.:.|.:         .|  :|.|......  :..|:.......||  :...||..
Human  1297 VQQLCSLIPNQNAAFS---------KCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTC 1352

  Fly    85 QVSGSKI--WQMERSC-MCCQESGEREAAVSLFCPKVKPGERKFKKVLTKAPLE-CMCRPCTSIE 145
            |..|..:  |:...|| :.|..:...|:.||:..|:.  ...:.|...:...:| |.|.....:.
Human  1353 QTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRC--AAIRLKSDCSHYCVEGCHCDAGYVLN 1415

  Fly   146 -ESGIIPQEIAGYSD 159
             :|.|:|.....|||
Human  1416 GKSCILPHSCGCYSD 1430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Burs	NP_650983.1	GHB_like	50..138	CDD:419725	21/97 (22%)
TECTA	NP_005413.2	NIDO	98..254	CDD:214712
		VWD	322..478	CDD:278521
		C8	517..591	CDD:214843
		TIL	597..650	CDD:280072
		VWC	652..706	CDD:302663
		VWD	703..865	CDD:214566
		C8	905..981	CDD:214843
		TIL	984..1036	CDD:280072
		VWD	1100..1258	CDD:278521
		C8	1298..1368	CDD:285899	15/78 (19%)
		TIL	1372..1425	CDD:280072	12/54 (22%)
		VWD	1487..1639	CDD:278521
		C8	1684..1757	CDD:214843
		ZP	1805..2057	CDD:214579
		Zona_pellucida	1937..2057	CDD:278526
		FXa_inhibition	2089..2121	CDD:291342
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900