DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Burs and becn1

DIOPT Version :9

Sequence 1:	NP_650983.1	Gene:	Burs / 42560	FlyBaseID:	FBgn0038901	Length:	173	Species:	Drosophila melanogaster
Sequence 2:	NP_001029112.1	Gene:	becn1 / 619357	XenbaseID:	XB-GENE-999318	Length:	445	Species:	Xenopus tropicalis

Alignment Length:	109	Identity:	27/109 - (24%)
Similarity:	41/109 - (37%)	Gaps:	20/109 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 SFACVGRCASYIQVSGS-KIWQMERSCMCCQESGEREAAVSLFCPKVKPG---------ERKFKK 127
            ||.| .||:..:::..| ||  :::..|      :...|..:....||||         |..|.:
Frog    12 SFVC-QRCSQPLKLDTSFKI--LDKVTM------QELTAPLVTTAAVKPGDIQEVDSNIEETFAE 67

  Fly   128 VLTKAPLECMCRPCTSIE-ESGIIPQEIAGYSDEGPLNNHFRRI 170
            ..|......:..|...:. ||......|...||.|.:.|..||:
Frog    68 NRTDGVSRRLIPPARMMSTESATSFTLIGEASDGGTMENLSRRL 111

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Burs	NP_650983.1	GHB_like	50..138	CDD:419725	17/74 (23%)
becn1	NP_001029112.1	BH3	102..124	CDD:373713	4/10 (40%)
		BH3. /evidence=ECO:0000250	103..122		3/9 (33%)
		APG6_N	130..256	CDD:375248
		Evolutionary conserved domain (ECD). /evidence=ECO:0000250\|UniProtKB:Q14457	240..445
		APG6	259..440	CDD:367821
		Required for membrane-association. /evidence=ECO:0000250\|UniProtKB:Q14457	420..445
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900