DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Burs and kcp

DIOPT Version :9

Sequence 1:	NP_650983.1	Gene:	Burs / 42560	FlyBaseID:	FBgn0038901	Length:	173	Species:	Drosophila melanogaster
Sequence 2:	XP_697494.6	Gene:	kcp / 569039	ZFINID:	ZDB-GENE-070705-443	Length:	2200	Species:	Danio rerio

Alignment Length:	167	Identity:	39/167 - (23%)
Similarity:	56/167 - (33%)	Gaps:	48/167 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RHLLRHENNKVFVLILLYCVLVSILKLCTAQPDSSVAAT--DNDITHLGD---DCQVTPVIHVLQ 62
            :|.:.|.::.            |...:|| ||.|:..||  .|::....|   .||...:.....
Zfish  1648 KHNILHSSSD------------SCCPVCT-QPLSNCTATLIGNEVLATDDPCFTCQCKDLTWTCV 1699

  Fly    63 YPGCVP-------KPIPSFACVGRC------ASYIQVSGSKIW-QMERSCMCC------QESGER 107
            :.||.|       :..|..:|...|      .|..:|.....| ..|..|..|      .|...:
Zfish  1700 HRGCPPLSCSPSDQHTPPDSCCPICDVCVLEGSNTRVPDGHRWTDKENECTTCICNKGHIECDLQ 1764

  Fly   108 EAAVSLFCPKVKPGERKFKKVLTKAPLECMCRPCTSI 144
            |.| .|.||.        ..|..|.|.:| |:.||.:
Zfish  1765 ECA-PLQCPD--------GSVKVKNPGKC-CQECTEV 1791

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Burs	NP_650983.1	GHB_like	50..138	CDD:419725	25/110 (23%)
kcp	XP_697494.6	LamG	38..>188	CDD:304605
		VWC	365..418	CDD:302663
		VWC	424..480	CDD:302663
		VWC	540..596	CDD:302663
		VWC	599..655	CDD:302663
		VWC	<681..714	CDD:302663
		VWC	778..836	CDD:302663
		VWC	891..947	CDD:302663
		VWC	1305..1361	CDD:302663
		VWC	1422..1478	CDD:302663
		VWC	1598..1663	CDD:302663	3/26 (12%)
		VWC	1803..1860	CDD:278520
		VWD	1867..2016	CDD:278521
		C8	2059..2128	CDD:285899
		TIL	2139..2192	CDD:280072
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900