DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Burs and fras1

DIOPT Version :9

Sequence 1:	NP_650983.1	Gene:	Burs / 42560	FlyBaseID:	FBgn0038901	Length:	173	Species:	Drosophila melanogaster
Sequence 2:	XP_005165392.1	Gene:	fras1 / 563428	ZFINID:	ZDB-GENE-060526-68	Length:	4003	Species:	Danio rerio

Alignment Length:	149	Identity:	35/149 - (23%)
Similarity:	45/149 - (30%)	Gaps:	43/149 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 TAQPDSSVAATDNDITHLGDDCQVTPVIHVLQYPGCVPK-PIPSF--------ACVGRCASYIQV 86
            |.||||             ..|...|..|.|....|.|: |...:        ||...|||   .
Zfish   566 TCQPDS-------------PSCMSCPAEHALHQGKCAPQCPAQYYKDDHGRCQACHSSCAS---C 614

  Fly    87 SGSKIWQMERSC---------MCCQESGEREAAVSLFCPKVKPGERKFKKVLTKAPLECMCRPCT 142
            ||..:... .||         .|.:..||...:.:..|.......|     :...|....|..|.
Zfish   615 SGPAVSHC-TSCSKALILNQGQCVESCGEGLFSRAGHCHSCHSSCR-----VCVGPDSSDCTQCV 673

  Fly   143 SIEESGIIPQEIAGYSDEG 161
            .:||. :.||.  |:...|
Zfish   674 KMEEV-LQPQN--GHVSHG 689

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Burs	NP_650983.1	GHB_like	50..138	CDD:419725	22/105 (21%)
fras1	XP_005165392.1	VWC	26..85	CDD:278520
		VWC	93..150	CDD:278520
		VWC	157..214	CDD:278520
		VWC	219..276	CDD:278520
		VWC	283..340	CDD:278520
		VWC	364..414	CDD:302663
		FU	419..465	CDD:238021
		Furin-like_2	424..512	CDD:292535
		FU	461..503	CDD:214589
		FU	507..551	CDD:214589
		GF_recep_IV	512..669	CDD:291509	27/124 (22%)
		FU	555..597	CDD:214589	12/43 (28%)
		Furin-like	588..762	CDD:279142	26/114 (23%)
		FU	602..645	CDD:214589	12/46 (26%)
		FU	648..700	CDD:214589	11/50 (22%)
		FU	704..748	CDD:214589
		Furin-like	737..911	CDD:279142
		FU	754..796	CDD:214589
		FU	855..897	CDD:214589
		Furin-like	888..1054	CDD:279142
		FU	950..994	CDD:214589
		FU	1044..1086	CDD:214589
		Cadherin_3	<1097..1196	CDD:292802
		Cadherin_3	1166..1306	CDD:292802
		Cadherin_3	1406..1538	CDD:292802
		Cadherin_3	1526..1689	CDD:292802
		Cadherin_3	1658..1811	CDD:292802
		Cadherin_3	1777..1934	CDD:292802
		Cadherin_3	1901..2056	CDD:292802
		Cadherin_3	2025..2175	CDD:292802
		Cadherin_3	2144..2290	CDD:292802
		Cadherin_3	2258..2403	CDD:292802
		Cadherin_3	2372..2534	CDD:292802
		Calx-beta	2550..2647	CDD:295344
		Calx-beta	2672..2771	CDD:295344
		Calx-beta	2795..2891	CDD:295344
		Calx-beta	2917..3008	CDD:295344
		Calx-beta	3036..3130	CDD:295344
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900