DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Burs and Crim1

DIOPT Version :9

Sequence 1:	NP_650983.1	Gene:	Burs / 42560	FlyBaseID:	FBgn0038901	Length:	173	Species:	Drosophila melanogaster
Sequence 2:	NP_001162574.1	Gene:	Crim1 / 298744	RGDID:	1308710	Length:	1037	Species:	Rattus norvegicus

Alignment Length:	157	Identity:	39/157 - (24%)
Similarity:	50/157 - (31%)	Gaps:	48/157 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 CVLVSILKLCTAQPDSSVAATDNDITHLGDDCQVTPVIHVLQYPGC-----VPKP---IPSFACV 77
            |.|::    |      .|.|..|.....|..|           |.|     |.||   .||. |.
  Rat   638 CALIT----C------PVPACGNPTIRPGQCC-----------PSCADDFVVQKPELSTPSI-CH 680

  Fly    78 GRCASYIQVSGSKIWQMERSCMCCQESG----EREAAVSLFCPKVKPGERKFKKVLTKAPLECMC 138
            .....|. |.| :.|.::....|...||    |.|....|.|......:.......|:.||:
  Rat   681 APGGEYF-VEG-ETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTEDPLQ--- 740

  Fly   139 RPCTSIEESGIIPQEIAGY--SDEGPL 163
             |.||..||      :..|  :|||.:
  Rat   741 -PSTSHNES------VPSYCRNDEGDI 760

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Burs	NP_650983.1	GHB_like	50..138	CDD:419725	23/99 (23%)
Crim1	NP_001162574.1	IB	37..>95	CDD:197525
		VWC	336..390	CDD:214564
		VWC	403..456	CDD:214564
		Antistasin	567..592	CDD:280912
		VWC	612..662	CDD:302663	9/44 (20%)
		VWC	683..734	CDD:302663	11/52 (21%)
		VWC	758..808	CDD:302663	1/3 (33%)
		VWC	819..873	CDD:302663
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900